Primary tumors actively and specifically prime pre-metastatic niches (PMNs), the future sites
of organotropic metastasis, preparing these distant microenvironments for disseminated …

Metabolic endotoxemia is a condition in which blood lipopolysaccharide (LPS) levels are
elevated, regardless of the presence of obvious infection. It has been suggested to lead to …

Distant metastasis is a primary cause of mortality and contributes to poor surgical outcomes
in cancer patients. Before the development of organ-specific metastasis, the formation of a …

Cancer metastasis is the leading cause of mortality in patients with cancer. Theories have
been developed to explain the causes and principles of metastasis. Metastasis is attributed …

Abstract S100A8 and S100A9 are Ca 2+ binding proteins that belong to the S100 family.
Primarily expressed in neutrophils and monocytes, S100A8 and S100A9 play critical roles in …

Licorice (Glycyrrhiza glabra) is a well-known natural herb used to treat different ailments
since ancient times. Glycyrrhizin (GL), which is the primary triterpenoid compound of licorice …

Background Immune checkpoint inhibitor-related cardiotoxicity is one of the most lethal
adverse effects, and thus, the identification of underlying mechanisms for developing …

The coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). According to the World Health …

Regulation of gut microbiota and its impact on human health is the theme of intensive
research. The incidence and prevalence of atrial fibrillation (AF) are continuously escalating …

Background Obesity is a significant risk factor for atrial fibrillation (AF), and the gut
microbiota is closely related to obesity-induced diseases. However, whether the gut …