Tuberculosis (TB) remains a prominent health concern worldwide. Besides extensive
research and vaccinations available, attempts to control the pandemic are cumbersome due …

Human tuberculosis (TB) is amongst the oldest and deadliest human bacterial diseases that
pose major health, social and economic burden at a global level. Current regimens for TB …

Foam cells are lipid-laden macrophages that contribute to the inflammation and tissue
damage associated with many chronic inflammatory disorders. Although foam cell …

Abstract Background and Objectives: Genome-scale metabolic networks (GEMs) represent a
valuable modeling and computational tool in the broad field of systems biology. Their ability …

Clavulanic acid (CA) is an irreversible β-lactamase enzyme inhibitor with a weak
antibacterial activity produced by Streptomyces clavuligerus (S. clavuligerus). CA is typically …

Metabolism underpins the pathogenic strategy of the causative agent of TB, Mycobacterium
tuberculosis (Mtb), and therefore metabolic pathways have recently re-emerged as attractive …

The molecule (2 S)-naringenin is a scaffold molecule with several nutraceutical properties.
Currently,(2 S)-naringenin is obtained through chemical synthesis and plant isolation …

Streptomyces clavuligerus (S. clavuligerus) is a filamentous Gram-positive bacterial
producer of the β-lactamase inhibitor clavulanic acid (CA). Antibiotics biosynthesis and …

The in vivo microenvironment of bacterial pathogens is often characterized by nutrient
limitation. Consequently, conventional rich in vitro culture conditions used widely to evaluate …

Streptomyces clavuligerus is a filamentous Gram-positive bacterial producer of the β-
lactamase inhibitor clavulanic acid. Antibiotics biosynthesis in the Streptomyces genus is …