Physiology of astroglia

A Verkhratsky, M Nedergaard - Physiological reviews, 2018 - journals.physiology.org
Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …

Oxidative stress and impaired oligodendrocyte precursor cell differentiation in neurological disorders

J Spaas, L Van Veggel, M Schepers, A Tiane… - Cellular and Molecular …, 2021 - Springer
Oligodendrocyte precursor cells (OPCs) account for 5% of the resident parenchymal central
nervous system glial cells. OPCs are not only a back-up for the loss of oligodendrocytes that …

Oligodendrocyte development and plasticity

DE Bergles, WD Richardson - Cold Spring Harbor …, 2016 - cshperspectives.cshlp.org
Oligodendrocyte precursor cells (OPCs) originate in the ventricular zones (VZs) of the brain
and spinal cord and migrate throughout the developing central nervous system (CNS) …

Single-cell transcriptomics uncovers glial progenitor diversity and cell fate determinants during development and gliomagenesis

Q Weng, J Wang, J Wang, D He, Z Cheng, F Zhang… - Cell stem cell, 2019 - cell.com
The identity and degree of heterogeneity of glial progenitors and their contributions to brain
tumor malignancy remain elusive. By applying lineage-targeted single-cell transcriptomics …

NG 2‐glia and their functions in the central nervous system

L Dimou, V Gallo - Glia, 2015 - Wiley Online Library
In the central nervous system, NG2‐glia represent a neural cell population that is distinct
from neurons, astrocytes, and oligodendrocytes. While in the past the main role ascribed to …

[HTML][HTML] Olig2 targets chromatin remodelers to enhancers to initiate oligodendrocyte differentiation

Y Yu, Y Chen, B Kim, H Wang, C Zhao, X He, L Liu… - Cell, 2013 - cell.com
Establishment of oligodendrocyte identity is crucial for subsequent events of myelination in
the CNS. Here, we demonstrate that activation of ATP-dependent SWI/SNF chromatin …

bHLH factors in self-renewal, multipotency, and fate choice of neural progenitor cells

I Imayoshi, R Kageyama - Neuron, 2014 - cell.com
Multipotent neural progenitor cells (NPCs) undergo self-renewal while producing neurons,
astrocytes, and oligodendrocytes. These processes are controlled by multiple basic helix …

Diverse subtypes of astrocytes and their development during corticogenesis

H Tabata - Frontiers in neuroscience, 2015 - frontiersin.org
Astrocytes are one of the most abundant cell types in the mammalian central nervous
system, and are known to have a wide variety of physiological functions, including …

[HTML][HTML] Life-long oligodendrocyte development and plasticity

A Nishiyama, T Shimizu, A Sherafat… - Seminars in cell & …, 2021 - Elsevier
Oligodendrocyte precursor cells (OPCs) originate in localized germinal zones in the
embryonic neural tube, then migrate and proliferate to populate the entire central nervous …

From OPC to oligodendrocyte: an epigenetic journey

A Tiane, M Schepers, B Rombaut, R Hupperts… - Cells, 2019 - mdpi.com
Oligodendrocytes provide metabolic and functional support to neuronal cells, rendering
them key players in the functioning of the central nervous system. Oligodendrocytes need to …