Genetic predisposition and its heredity in the context of increased prevalence of dermatophytoses

S Gnat, D Łagowski, A Nowakiewicz - Mycopathologia, 2021 - Springer
Dermatophytosis is a widespread disease with high prevalence and a substantial economic
burden associated with costs of treatment. The pattern of this infectious disease covers a …

In vitro models of dermatophyte infection to investigate epidermal barrier alterations

É Faway, C Lambert de Rouvroit… - Experimental …, 2018 - Wiley Online Library
Fungal infections of the skin, known as dermatophytoses, are initiated at the epidermal
barrier and lead to dysfunctions of the stratum corneum and cornified skin appendages …

[HTML][HTML] New insights into genes, immunity, and the occurrence of dermatophytosis

MT García-Romero, R Arenas - Journal of Investigative Dermatology, 2015 - Elsevier
Fungal infections in humans are among the most prevalent diseases globally. Superficial
invasion by dermatophytes leads to skin, hair, and nail infection. Even though they have …

Genetic predisposition–understanding underlying mechanisms of onychomycosis

J Faergemann, O Correia, R Nowicki… - Journal of the …, 2005 - Wiley Online Library
Background There are numerous factors that predispose to onychomycosis including
genetic predisposition, diabetes mellitus, immunosuppression, vascular disease and …

Genetic predictors of susceptibility to dermatophytoses

SM Abdel-Rahman - Mycopathologia, 2017 - Springer
Countless observational studies conducted over the last century reveal that dermatophytes
infect humans of every age, race, gender, and socioeconomic status with strikingly high …

[HTML][HTML] Low DEFB4 copy number and high systemic hBD-2 and IL-22 levels are associated with dermatophytosis

SW Jaradat, S Cubillos, N Krieg, K Lehmann… - Journal of Investigative …, 2015 - Elsevier
Dermatophytes initiate dermatophytosis, but susceptibility to infection is dictated by host
genetic factors, although the role of some of these—such as human beta-defensin 2 (hBD-2) …

Onicomicosis: afección común de difícil tratamiento

N Mendoza, C Palacios… - Revista de la …, 2012 - revista.asocolderma.org.co
La onicomicosis es la enfermedad más frecuente de las uñas. Es una infección de la unidad
ungular causada por dermatofitos, mohos y levaduras, de los cuales, los primeros son los …

HLA‐DR6 association confers increased resistance to T. rubrum onychomycosis in Mexican Mestizos

D Asz‐Sigall, L López‐García… - International journal …, 2010 - Wiley Online Library
Background Onychomycosis is multifactorial in origin. Studies have suggested an autosomal
dominant pattern of inheritance and human leukocyte antigen DR4 (HLA‐DR4) has been …

[HTML][HTML] Analysis of genetic polymorphism of the HLA-B and HLA-DR loci in patients with dermatophytic onychomycosis and in their first-degree relatives

MT García-Romero, J Granados… - Actas Dermo …, 2012 - Elsevier
Onychomycosis is known to have predisposing factors and a high prevalence within families
that cannot be explained by within-family transmission. We determined the frequency of HLA …

Do genetic mutations and genotypes contribute to onychomycosis?

AK Gupta, FC Simpson, WC Brintnell - Dermatology, 2014 - karger.com
Background: The variability in susceptibility to onychomycosis for individuals exposed to the
same environmental risk factors raises the possibility that there may be individuals with a …