Introduction: In pharmaceutical design where future drugs are developed by targeting a
specific chosen protein, the evaluation of ligand affinity is crucial. For this very purpose are a …

Abstract Glucose transporter 1 (GLUT1) overexpression in tumor cells is a potential target for
drug therapy, but few studies have reported screening GLUT1 inhibitors from natural or …

Capillary electrophoresis (CE) has attracted lots of attention due to its simplicity, low sample
consumption, low solvent volume, high resolution, and high speed. Based on these …

Breast cancer is the one of the most frequent causes of female cancer mortality. KDM5A, a
histone demethylase, can increase the proliferation, metastasis, and drug resistance of …

Silicon quantum dots have become one of the most popular nanomaterials in biological
applications for their excellent biocompatibility and optical properties. Herein, we …

The development of simple, easy-to-operate and real-time detection methods for the active
ingredients in herbal medicines has aroused growing interest owing to their pivotal health …

The interaction between AFF4 and the P-TEFb cyclin T1 (CCNT1) subunit is linked with
various human cancers, including triple-negative breast cancer (TNBC). However, the …

The drug–target protein interaction is the basis of drug screening and precise therapy in
modern clinical medicine. How to acquire the information about the drug–target protein …

The upregulation of glucose transporter (GLUT) is a typical pathological marker in numerous
cancer types and a potential target for anti-cancer drug therapy. We developed a cell …

Selective and sensitive detection of bioflavonoid glycosides remains a great challenge
because the coexistence of their analogues in real samples will produce serious …