The CB2 receptor and its role as a regulator of inflammation

C Turcotte, MR Blanchet, M Laviolette… - Cellular and Molecular …, 2016 - Springer
The CB 2 receptor is the peripheral receptor for cannabinoids. It is mainly expressed in
immune tissues, highlighting the possibility that the endocannabinoid system has an …

Integrating endocannabinoid signaling and cannabinoids into the biology and treatment of posttraumatic stress disorder

MN Hill, P Campolongo, R Yehuda… - …, 2018 - nature.com
Exposure to stress is an undeniable, but in most cases surmountable, part of life. However,
in certain individuals, exposure to severe or cumulative stressors can lead to an array of …

Regulation of inflammation by cannabinoids, the endocannabinoids 2-arachidonoyl-glycerol and arachidonoyl-ethanolamide, and their metabolites

C Turcotte, F Chouinard, JS Lefebvre… - Journal of Leucocyte …, 2015 - academic.oup.com
Arachidonoyl-glycerol (2-AG) and arachidonyl-ethanolamide (AEA) are endocannabinoids
that have been implicated in many physiologic disorders, including obesity, metabolic …

The endocannabinoid system and physical exercise

D Matei, D Trofin, DA Iordan, I Onu… - International journal of …, 2023 - mdpi.com
The endocannabinoid system (ECS) is involved in various processes, including brain
plasticity, learning and memory, neuronal development, nociception, inflammation, appetite …

Non-steroidal anti-inflammatory drugs, pharmacology, and COVID-19 infection

J Micallef, T Soeiro, AP Jonville-Bera… - Therapies, 2020 - Elsevier
Non-steroidal anti-inflammatory drugs (NSAIDs) have an optional prescription status that
has resulted in frequent use, in particular for the symptomatic treatment of fever and non …

Targeting cannabinoid signaling in the immune system:“High”-ly exciting questions, possibilities, and challenges

A Oláh, Z Szekanecz, T Bíró - Frontiers in Immunology, 2017 - frontiersin.org
It is well known that certain active ingredients of the plants of Cannabis genus, ie, the
“phytocannabinoids”[pCBs; eg,(−)-trans-Δ9-tetrahydrocannabinol (THC),(−)-cannabidiol …

Detrimental cross-talk between sepsis and acute kidney injury: new pathogenic mechanisms, early biomarkers and targeted therapies

S Dellepiane, M Marengo, V Cantaluppi - Critical Care, 2016 - Springer
This article is one of ten reviews selected from the Annual Update in Intensive Care and
Emergency medicine 2016. Other selected articles can be found online at http://www …

Cannabinoid receptor type 2: a possible target in SARS-CoV-2 (CoV-19) infection?

F Rossi, C Tortora, M Argenziano, A Di Paola… - International Journal of …, 2020 - mdpi.com
In late December 2019, a novel coronavirus (SARS-CoV-2 or CoV-19) appeared in Wuhan,
China, causing a global pandemic. SARS-CoV-2 causes mild to severe respiratory tract …

β-Caryophyllene, a natural dietary CB2 receptor selective cannabinoid can be a candidate to target the trinity of infection, immunity, and inflammation in Covid-19

NK Jha, C Sharma, HM Hashiesh… - Frontiers in …, 2021 - frontiersin.org
Coronavirus disease (COVID-19), caused by novel severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), is an ongoing pandemic and presents a public health …

Stress related shift toward inflammaging in cosmonauts after long-duration space flight

JI Buchheim, S Matzel, M Rykova, G Vassilieva… - Frontiers in …, 2019 - frontiersin.org
Space flight exerts a specific conglomerate of stressors on humans that can modulate the
immune system. The mechanism remains to be elucidated and the consequences for …