Despite recent medical advances, atherosclerosis is a global burden accounting for
numerous deaths and hospital admissions. Immune-mediated inflammation is a major …

Atherosclerosis is an immune-mediated chronic inflammatory disease that leads to the
development of fatty plaques in the arterial walls, ultimately increasing the risk of thrombosis …

Atherosclerosis is a chronic inflammatory disease of the artery wall. Adaptive immunity plays
a key role in the pathogenesis of atherosclerosis. Recently, modulation of the immune …

Numerous cardiovascular disorders have atherosclerosis as their pathological
underpinning. Numerous studies have demonstrated that, with the aid of pattern recognition …

Atherosclerosis, an inflammatory disorder involving innate and adaptive immune responses
with both atheroprotective and proatherogenic roles, is a life wasting and economic …

The pathogenesis of atherosclerotic inflammation is a multi-step process defined by the
interweaving of excess modified lipid particles, monocyte-macrophages populations, and …

Cardiovascular diseases (CVD) remain the major cause of morbidity and mortality in
Europe. The clinical complications associated to arterial wall rupture involve intimal cap …

Substantial data from experimental and clinical investigation support the role of immune-
mediated mechanisms in atherogenesis, with immune systems responding to many …

Objective: Emerging evidence suggests that C3aR (C3a anaphylatoxin receptor) signaling
has protective roles in various inflammatory-related diseases. However, its role in …

Background—Tissue factor (TF) and coagulation proteases are involved in promoting
atherosclerosis, but the molecular and cellular bases for their involvement are unknown …