The rapid emergence and dissemination of antimicrobial-resistant microorganisms in ICUs
worldwide constitute a problem of crisis dimensions. The root causes of this problem are …

Background The first publication of this review in Issue 3, 2005 included studies up to
November 2003. This update adds studies to December 2006 and focuses on application of …

Fever may be the only clinical symptom at the onset of infection in neutropenic cancer
patients undergoing myelosuppressive chemotherapy. A prompt and evidence-based …

Some of the most common infectious diseases are caused by bacteria that naturally colonise
humans asymptomatically. Combating these opportunistic pathogens requires an …

An increasing variety of indicators of antimicrobial usage has become available in human
and veterinary medicine, with no consensus on the most appropriate indicators to be used …

Bacterial resistance to antibiotics is a growing clinical problem and public health threat.
Antibiotic use is a known risk factor for the emergence of antibiotic resistance, but …

Introduction In the time of increasing resistance and paucity of new drug development there
is a growing need for strategies to enhance rational use of antibiotics in German and …

The community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA)
epidemic in the United States is largely attributable to the meteoric rise of a single clone …

Objectives 'National Special Stewardship in the Clinical Use of Antibiotics' was put forward
in July 2011 in China. We aimed to retrospectively evaluate the impact of antimicrobial …

Abstract Objectives Methicillin-resistant Staphylococcus aureus (MRSA) is a major
nosocomial pathogen worldwide. A wide range of factors have been suggested to influence …