Galectin-9 as a biomarker of disease severity
Abstract Galectin-9 (Gal-9) is a β-galactoside binding lectin known for its immunomodulatory
role in various microbial infections. Gal-9 is expressed in all organ systems and localized in …
role in various microbial infections. Gal-9 is expressed in all organ systems and localized in …
Galectins and immune responses—just how do they do those things they do?
S Thiemann, LG Baum - Annual review of immunology, 2016 - annualreviews.org
Galectins are a family of mammalian carbohydrate-binding proteins expressed by many cell
types. Galectins can function intracellularly and can also be secreted to bind to cell surface …
types. Galectins can function intracellularly and can also be secreted to bind to cell surface …
Galectin-3 and aldosterone as potential tandem biomarkers in pulmonary arterial hypertension
Background Several studies have identified circulating biomarkers to be associated with the
presence and severity of pulmonary arterial hypertension (PAH). Recent evidence supports …
presence and severity of pulmonary arterial hypertension (PAH). Recent evidence supports …
[HTML][HTML] Novel fibro-inflammation markers in assessing left atrial remodeling in non-valvular atrial fibrillation
O Sonmez, FU Ertem, MA Vatankulu… - … medical journal of …, 2014 - ncbi.nlm.nih.gov
Background Structural remodeling is associated with the fibroinflammatory process in the
atrial extracellular matrix. In the present study we aimed to investigate whether serum levels …
atrial extracellular matrix. In the present study we aimed to investigate whether serum levels …
Macrophage inflammatory markers are associated with subclinical carotid artery disease in women with human immunodeficiency virus or hepatitis C virus infection
Objective—Infection with hepatitis C virus (HCV) or human immunodeficiency virus (HIV)
may be associated with atherosclerosis and vascular disease. Macrophages are a major …
may be associated with atherosclerosis and vascular disease. Macrophages are a major …
Is galectin-3 a biomarker, a player—or both—in the presence of coronary atherosclerosis?
G Aksan, Ö Gedikli, K Keskin, G Nar… - Journal of …, 2016 - journals.sagepub.com
Atherosclerosis is a complex process mediated by leukocytes, macrophages and various
inflammatory markers. Galectin-3 is secreted by activated macrophages and is involved in …
inflammatory markers. Galectin-3 is secreted by activated macrophages and is involved in …
Galectins: major signaling modulators inside and outside the cell
D Compagno, FM Jaworski, L Gentilini… - Current molecular …, 2014 - ingentaconnect.com
Galectins control cell behavior by acting on different signaling pathways. Most of the
biological activities ascribed to these molecules rely upon recognition of extracellular …
biological activities ascribed to these molecules rely upon recognition of extracellular …
Galectin-3 is a key hepatoprotective molecule against the deleterious effect of cisplatin
Aims Evaluate the role of galectin-3 in the liver using an acute model of cisplatin-induced
toxicity. Material and methods Modified citrus pectin (MCP) treatment was used to inhibit …
toxicity. Material and methods Modified citrus pectin (MCP) treatment was used to inhibit …
Galectin-9 is a target for the treatment of cancer: A patent review
CF Rodrigues, FA Santos, LAA Amorim… - International Journal of …, 2024 - Elsevier
Galectins, which correspond to a group of proteins capable of recognizing and reversibly
binding to β-galactoside carbohydrates, have been the subject of innovation and …
binding to β-galactoside carbohydrates, have been the subject of innovation and …
Galectin-3 binding protein secreted by breast cancer cells inhibits monocyte-derived fibrocyte differentiation
To metastasize, tumor cells often need to migrate through a layer of collagen-containing scar
tissue which encapsulates the tumor. A key component of scar tissue and fibrosing diseases …
tissue which encapsulates the tumor. A key component of scar tissue and fibrosing diseases …