Glutamate is the predominant excitatory neurotransmitter in the central nervous system
(CNS) and glutamatergic transmission is critical for controlling neuronal activity Glutamate is …

Despite the essential role of the corticospinal tract (CST) in controlling voluntary movements,
successful regeneration of large numbers of injured CST axons beyond a spinal cord lesion …

Glutamate is the predominant excitatory neurotransmitter used by primary afferent synapses
and neurons in the spinal cord dorsal horn. Glutamate and glutamate receptors are also …

Smaller spinal cord injuries often allow some degree of spontaneous behavioral
improvements because of structural rearrangements within different descending fiber tracts …

Severe spinal cord injury in humans leads to a progressive neuronal dysfunction in the
chronic stage of the injury. This dysfunction is characterized by premature exhaustion of …

Impaired signaling via CX3CR1, the fractalkine receptor, promotes recovery after traumatic
spinal contusion injury in mice, a benefit achieved in part by reducing macrophage …

Motor and sensory proprioceptive axons reinnervate muscles after peripheral nerve
transections followed by microsurgical reattachment; nevertheless, motor coordination …

The ventral posterior nucleus of the thalamus (VP) receives two major sets of excitatory
inputs, one from the ascending somatosensory pathways originating in the dorsal horn …

ATP is known to be coreleased with glutamate at certain central synapses. However, the
nature of its release is controversial. Here, we demonstrate that ATP release from cultured …

Projection neurons belonging to the anterolateral system (ALS) underlie the perception of
pain, skin temperature and itch. Many ALS cells are located in laminae III-V of the dorsal …