Corticosteroids in acute lung injury: the dilemma continues
Acute lung injury (ALI) represents a serious heterogenous pulmonary disorder with high
mortality. Despite improved understanding of the pathophysiology, the efficacy of standard …
mortality. Despite improved understanding of the pathophysiology, the efficacy of standard …
American College of Rheumatology clinical guidance for multisystem inflammatory syndrome in children associated With SARS–CoV‐2 and hyperinflammation in …
LA Henderson, SW Canna, KG Friedman… - Arthritis & …, 2020 - Wiley Online Library
Objective To provide guidance on the management of multisystem inflammatory syndrome
in children (MIS‐C), a condition characterized by fever, inflammation, and multiorgan …
in children (MIS‐C), a condition characterized by fever, inflammation, and multiorgan …
American College of rheumatology clinical guidance for multisystem inflammatory syndrome in children associated with SARS–CoV‐2 and Hyperinflammation in …
LA Henderson, SW Canna, KG Friedman… - Arthritis & …, 2021 - Wiley Online Library
Objective To provide guidance on the management of Multisystem Inflammatory Syndrome
in Children (MIS‐C), a condition characterized by fever, inflammation, and multiorgan …
in Children (MIS‐C), a condition characterized by fever, inflammation, and multiorgan …
Safety and efficacy of corticosteroids in ARDS patients: a systematic review and meta-analysis of RCT data
X Chang, S Li, Y Fu, H Dang, C Liu - Respiratory research, 2022 - Springer
Purpose Acute respiratory distress syndrome (ARDS) is an acute and critical disease among
children and adults, and previous studies have shown that the administration of …
children and adults, and previous studies have shown that the administration of …
Exploring the heterogeneity of effects of corticosteroids on acute respiratory distress syndrome: a systematic review and meta-analysis
Introduction The effectiveness of corticosteroid therapy on the mortality of acute respiratory
distress syndrome (ARDS) remains under debate. We aimed to explore the grounds for the …
distress syndrome (ARDS) remains under debate. We aimed to explore the grounds for the …
General adaptation in critical illness: glucocorticoid receptor-alpha master regulator of homeostatic corrections
GU Meduri, GP Chrousos - Frontiers in endocrinology, 2020 - frontiersin.org
In critical illness, homeostatic corrections representing the culmination of hundreds of
millions of years of evolution, are modulated by the activated glucocorticoid receptor alpha …
millions of years of evolution, are modulated by the activated glucocorticoid receptor alpha …
[HTML][HTML] Balancing evidence and frontline experience in the early phases of the COVID-19 pandemic: current position of the Italian Society of Anti-Infective Therapy …
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the
causative agent of coronavirus disease 2019 (COVID-19), which has rapidly become …
causative agent of coronavirus disease 2019 (COVID-19), which has rapidly become …
An exploratory reanalysis of the randomized trial on efficacy of corticosteroids as rescue therapy for the late phase of acute respiratory distress syndrome
GU Meduri, L Bridges, RAC Siemieniuk… - Critical Care …, 2018 - journals.lww.com
Objectives: In the Acute Respiratory Distress Syndrome Network randomized controlled trial,
methylprednisolone treatment was associated with increased return to mechanical …
methylprednisolone treatment was associated with increased return to mechanical …
Effects of different corticosteroid doses and durations on smoke inhalation-induced acute lung injury and pulmonary fibrosis in the rat
LC Song, XX Chen, JG Meng, M Hu, JB Huan… - International …, 2019 - Elsevier
Excessive inflammation induced by cytokine storm and coagulation disorders is considered
the primary characteristic of smoke inhalation-induced acute lung injury (SI-ALI) …
the primary characteristic of smoke inhalation-induced acute lung injury (SI-ALI) …
[HTML][HTML] Early application of low‑dose glucocorticoid improves acute respiratory distress syndrome: A meta‑analysis of randomized controlled trials
ZG Yang, XL Lei, XL Li - Experimental and Therapeutic …, 2017 - spandidos-publications.com
Previous clinical trials have investigated the effect of glucocorticoid therapy in acute
respiratory distress syndrome (ARDS), with controversial results, particularly with regard to …
respiratory distress syndrome (ARDS), with controversial results, particularly with regard to …