New insights into an old protein: the functional diversity of mammalian glyceraldehyde-3-phosphate dehydrogenase

MA Sirover - Biochimica et Biophysica Acta (BBA)-Protein Structure …, 1999 - Elsevier
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) was considered a classical
glycolytic protein examined for its pivotal role in energy production. It was also used as a …

Oxidatively modified glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and Alzheimer's disease: many pathways to neurodegeneration

DA Butterfield, SS Hardas… - Journal of Alzheimer's …, 2010 - content.iospress.com
Abstract Recently, the oxidoreductase, glyceraldehyde-3-phosphate dehydrogenase
(GAPDH), has become a subject of interest as more and more studies reveal a surfeit of …

Finding one's way in proteomics: a protein species nomenclature

H Schlüter, R Apweiler, HG Holzhütter… - Chemistry Central …, 2009 - Springer
Our knowledge of proteins has greatly improved in recent years, driven by new technologies
in the fields of molecular biology and proteome research. It has become clear that from a …

Role of the glycolytic protein, glyceraldehyde‐3‐phosphate dehydrogenase, in normal cell function and in cell pathology

MA Sirover - Journal of cellular biochemistry, 1997 - Wiley Online Library
The glycolytic protein glyceraldehyde‐3‐phosphate dehydrogenase (GAPDH) appeared to
be an archtypical protein of limited excitement. However, independent studies from a …

Potential role of nuclear translocation of glyceraldehyde-3-phosphate dehydrogenase in apoptosis and oxidative stress

Z Dastoor, JL Dreyer - Journal of cell science, 2001 - journals.biologists.com
Recent studies indicating a role of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in
apoptosis or oxidative stress has been reported. Using confocal laser-scanning microscopy …

Single-gene disorders: what role could moonlighting enzymes play?

G Sriram, JA Martinez, ERB McCabe, JC Liao… - The American Journal of …, 2005 - cell.com
Single-gene disorders with" simple" Mendelian inheritance do not always imply that there
will be an easy prediction of the phenotype from the genotype, which has been shown for a …

Human DNA repair genes

A Ronen, BW Glickman - Environmental and molecular …, 2001 - Wiley Online Library
DNA repair systems are essential for the maintenance of genome integrity. Consequently,
the disregulation of repair genes can be expected to be associated with significant …

Dinucleoside polyphosphates—friend or foe?

AG McLennan - Pharmacology & therapeutics, 2000 - Elsevier
Despite being known for over 30 years, the functions of the dinucleoside polyphosphates,
such as diadenosine 5′, 5′′′-P1, P4-tetraphosphate (Ap4A) and diadenosine 5 …

Oxidative modifications of glyceraldehyde-3-phosphate dehydrogenase play a key role in its multiple cellular functions

NR Hwang, SH Yim, YM Kim, J Jeong… - Biochemical …, 2009 - portlandpress.com
Knowledge of the cellular targets of ROS (reactive oxygen species) and their regulation is an
essential prerequisite for understanding ROS-mediated signalling. GAPDH (glyceraldehyde …

[PDF][PDF] Seasonal effects on gene expression, cleavage timing, and developmental competence of bovine preimplantation embryos

M Gendelman, A Aroyo, S Yavin, Z Roth - Reproduction, 2010 - academia.edu
We examined the association between season and expression of genes involved in early
embryonic development with an emphasis on cleavage rate and timing of the first embryonic …