Complex diseases are defined to be determined by multiple genetic and environmental
factors alone as well as in interactions. To analyze interactions in genetic data, many …

Genomics can reveal essential features about the demographic evolution of a population
that may not be apparent from historical elements. In recent years, there has been a …

As we enter the 21st century, a new era of nutrition in the prevention and treatment of
disease emerges. Clinical nutrition involves the integration of diet, genetics, environment …

Background The beta2-adrenergic receptor (ADRB2) gene polymorphism has been
implicated in susceptibility to obesity, but study results are still controversial. Objective The …

Results: The most prevalent leptin/leptin receptor genes (LEP/LEPR) and ghrelin/ghrelin
receptor genes (GHRL/GHSR) single nucleotide polymorphisms studied were LEP G …

OBJECTIVE: The aim of the study was to investigate whether adiposity and metabolic
markers, such as leptin, glucose, and lipids, are influenced by leptin (LEP) and leptin …

Although genome-wide association studies (GWAS) have identified a significant number of
single-nucleotide polymorphisms (SNPs) associated with many complex human traits, the …

BACKGROUND: Obesity associated insulin resistance is a major risk factor for type 2
diabetes mellitus. Resistin is recently reported to provide a link between obesity, insulin …

Perilipin proteins were discovered in the adipocyte, where they regulate lipid storage and
lipolysis. Animal knockout models provided initial evidence of the critical role of perilipin 1 …

The prevalence of childhood obesity is increasing in many countries and confers risks for
early type 2 diabetes, cardiovascular disease and metabolic syndrome. In the presence of …