Evaluating the promise of inclusion of African ancestry populations in genomics
AR Bentley, SL Callier, CN Rotimi - NPJ genomic medicine, 2020 - nature.com
The lack of representation of diverse ancestral backgrounds in genomic research is well-
known, and the resultant scientific and ethical limitations are becoming increasingly …
known, and the resultant scientific and ethical limitations are becoming increasingly …
The impact of HLA polymorphism on herpesvirus infection and disease
Abstract Human Leukocyte Antigens (HLA) are cell surface molecules, central in
coordinating innate and adaptive immune responses, that are targets of strong diversifying …
coordinating innate and adaptive immune responses, that are targets of strong diversifying …
Association of novel locus with rheumatic heart disease in Black African individuals: findings from the RHDGen study
Importance Rheumatic heart disease (RHD), a sequela of rheumatic fever characterized by
permanent heart valve damage, is the leading cause of cardiac surgery in Africa. However …
permanent heart valve damage, is the leading cause of cardiac surgery in Africa. However …
Distinct genetic architectures and environmental factors associate with host response to the γ2-herpesvirus infections
Kaposi's sarcoma-associated herpesvirus (KSHV) and Epstein-Barr Virus (EBV) establish
life-long infections and are associated with malignancies. Striking geographic variation in …
life-long infections and are associated with malignancies. Striking geographic variation in …
Tackling the lack of diversity in cancer research
C Molina-Aguilar… - Disease Models & …, 2023 - journals.biologists.com
Despite the clear benefit of studying biological samples from diverse genetic backgrounds
and geographical locations, our current knowledge of disease is mostly derived from the …
and geographical locations, our current knowledge of disease is mostly derived from the …
[HTML][HTML] Long noncoding RNA LINC00341 promotes the vascular smooth muscle cells proliferation and migration via miR-214/FOXO4 feedback loop
X Liu, BD Ma, S Liu, J Liu, BX Ma - American journal of …, 2019 - ncbi.nlm.nih.gov
Increasing evidences have indicated the vital roles of long noncoding RNA (lncRNA) in the
atherosclerosis. However, whether lncRNA LINC00341 play pivotal roles in the vascular …
atherosclerosis. However, whether lncRNA LINC00341 play pivotal roles in the vascular …
Determinants of gammaherpesvirus shedding in saliva among Ugandan children and their mothers
Abstract Background Epstein-Barr virus (EBV) and Kaposi sarcoma–associated herpesvirus
(KSHV) are transmitted via saliva, but factors associated with salivary shedding are …
(KSHV) are transmitted via saliva, but factors associated with salivary shedding are …
EBNA-1 titer gradient in families with multiple sclerosis indicates a genetic contribution
JY Mescheriakova, GP van Nierop… - Neurology …, 2020 - AAN Enterprises
Objective In multiplex MS families, we determined the humoral immune response to Epstein-
Barr virus nuclear antigen 1 (EBNA-1)-specific immunoglobulin γ (IgG) titers in patients with …
Barr virus nuclear antigen 1 (EBNA-1)-specific immunoglobulin γ (IgG) titers in patients with …
Mendelian randomisation identifies priority groups for prophylactic EBV vaccination
Abstract Background Epstein Barr virus (EBV) infects~ 95% of the population worldwide and
is known to cause adverse health outcomes such as Hodgkin's, non-Hodgkin's lymphomas …
is known to cause adverse health outcomes such as Hodgkin's, non-Hodgkin's lymphomas …
Variation in the Human Leukocyte Antigen system and risk for endemic Burkitt lymphoma in northern Uganda
S Kirimunda, M Verboom, I Otim… - British journal of …, 2020 - Wiley Online Library
Endemic Burkitt lymphoma (eBL) is an aggressive childhood B‐cell lymphoma associated
with Plasmodium falciparum (Pf) malaria and Epstein–Barr virus (EBV) infections. Variation …
with Plasmodium falciparum (Pf) malaria and Epstein–Barr virus (EBV) infections. Variation …