Antibody–drug conjugates (ADCs) harness the highly specific targeting capabilities of an
antibody to deliver a cytotoxic payload to specific cell types. They have garnered …

Bioorthogonal chemistries enable researchers to interrogate biomolecules in living systems.
These reactions are highly selective and biocompatible, and can be performed in many …

Combining the selective targeting of tumor cells through antigen-directed recognition and
potent cell-killing by cytotoxic payloads, antibody-drug conjugates (ADCs) have emerged in …

In recent years, antibody-drug conjugates (ADCs) have become promising antitumor agents
to be used as one of the tools in personalized cancer medicine. ADCs are comprised of a …

The emergence of bioorthogonal reactions has greatly advanced research in the fields of
biology and medicine. They are not only valuable for labeling, tracking, and understanding …

Described is the spatiotemporally controlled labeling and patterning of biomolecules in live
cells through the catalytic activation of bioorthogonal chemistry with light, referred to as …

Peptide and protein selective modification at tyrosine residues has become an exploding
field of research as tyrosine constitutes a robust alternative to lysine and cysteine-targeted …

Chromophores that absorb in the tissue-penetrant far-red/near-infrared window have long
served as photocatalysts to generate singlet oxygen for photodynamic therapy. However, the …

Protein bioconjugation is an increasingly important field of research, with wide-ranging
applications in areas such as therapeutics and biomaterials. Traditional cysteine and lysine …

Click chemistry has been established rapidly as one of the most valuable methods for the
chemical transformation of complex molecules. Due to the rapid rates, clean conversions to …