[HTML][HTML] Dopamine receptors and neurodegeneration

C Rangel-Barajas, I Coronel, B Florán - Aging and disease, 2015 - ncbi.nlm.nih.gov
Dopamine (DA) is one of the major neurotransmitters and participates in a number of
functions such as motor coordination, emotions, memory, reward mechanism …

Roles of PI3K/AKT/GSK3 pathway involved in psychiatric illnesses

S Matsuda, Y Ikeda, M Murakami, Y Nakagawa, A Tsuji… - Diseases, 2019 - mdpi.com
Psychiatric illnesses may be qualified to the cellular impairments of the function for survival
or death in neurons, which may consequently appear as abnormalities in the neuroplasticity …

[HTML][HTML] A mega-analysis of genome-wide association studies for major depressive disorder

Major Depressive Disorder Working Group of … - Molecular …, 2013 - ncbi.nlm.nih.gov
Prior genome-wide association studies (GWAS) of major depressive disorder (MDD) have
met with limited success. We sought to increase statistical power to detect disease loci by …

Norepinephrine versus dopamine and their interaction in modulating synaptic function in the prefrontal cortex

B Xing, YC Li, WJ Gao - Brain research, 2016 - Elsevier
Among the neuromodulators that regulate prefrontal cortical circuit function, the
catecholamine transmitters norepinephrine (NE) and dopamine (DA) stand out as powerful …

Wnt Signaling: Role in Alzheimer Disease and Schizophrenia

NC Inestrosa, C Montecinos-Oliva… - Journal of Neuroimmune …, 2012 - Springer
Wnt signaling function starts during the development of the nervous system and is crucial for
synaptic plasticity in the adult brain. Clearly Wnt effects in synaptic and plastic processes are …

Wnt signaling networks in autism spectrum disorder and intellectual disability

V Kwan, BK Unda, KK Singh - Journal of neurodevelopmental disorders, 2016 - Springer
Background Genetic factors play a major role in the risk for neurodevelopmental disorders
such as autism spectrum disorders (ASDs) and intellectual disability (ID). The underlying …

Decreases in ganglion cell layer and inner plexiform layer volumes correlate better with disease severity in schizophrenia patients than retinal nerve fiber layer …

M Celik, A Kalenderoglu, AS Karadag… - European …, 2016 - cambridge.org
BackgroundOptic coherence tomography (OCT) is a new, contactless and fast neuroimaging
method. Previous studies have observed thinning of the retinal nerve fibre layer (RNFL) in …

Molecular and neuronal mechanisms underlying the effects of adolescent nicotine exposure on anxiety and mood disorders

SR Laviolette - Neuropharmacology, 2021 - Elsevier
Tobacco addiction is highly co-morbid with a variety of mental health conditions, including
schizophrenia, mood and anxiety disorders. Nicotine, the primary psychoactive compound in …

Wnt signaling in the central nervous system: new insights in health and disease

CA Oliva, C Montecinos-Oliva, NC Inestrosa - Progress in molecular …, 2018 - Elsevier
Since its discovery, Wnt signaling has been shown to be one of the most crucial
morphogens in development and during the maturation of central nervous system. Its action …

Modulation of synaptic plasticity in the cortex needs to understand all the players

CNJ Meunier, P Chameau, PM Fossier - Frontiers in synaptic …, 2017 - frontiersin.org
The prefrontal cortex (PFC) is involved in cognitive tasks such as working memory, decision
making, risk assessment and regulation of attention. These functions performed by the PFC …