Chemobrain in breast cancer: mechanisms, clinical manifestations, and potential interventions

GR Onzi, N D'Agustini, SC Garcia, SS Guterres… - Drug safety, 2022 - Springer
Among the potential adverse effects of breast cancer treatment, chemotherapy-related
cognitive impairment (CRCI) has gained increased attention in the past years. In this review …

Four decades of chemotherapy-induced cognitive dysfunction: Comprehensive review of clinical, animal and in vitro studies, and insights of key initiating events

A Dias-Carvalho, M Ferreira, R Ferreira, ML Bastos… - Archives of …, 2022 - Springer
Cognitive dysfunction has been one of the most reported and studied adverse effects of
cancer treatment, but, for many years, it was overlooked by the medical community …

Naringenin mitigates nanoparticulate-aluminium induced neuronal degeneration in brain cortex and hippocampus through downregulation of oxidative stress and …

R Rai, PL Kalar, D Jat, SK Mishra - Neurochemistry International, 2024 - Elsevier
Alumunium usage and toxicity has been a global concern especially an increased use of
nanoparticulated aluminum (Al-NPs) products from the environment and the workplace. Al …

Naringin: Biosynthesis and Pharmaceutical Applications.

P Sharma, V Kumar, P Guleria - Indian Journal of …, 2019 - search.ebscohost.com
Naringin is a plant flavonoid of huge medicinal importance. It is synthesized by the
phenylpropanoid pathway via seven enzyme catalysed steps from phenylalanine to prunin …

Carissa macrocarpa Leaves Polar Fraction Ameliorates Doxorubicin-Induced Neurotoxicity in Rats via Downregulating the Oxidative Stress and Inflammatory Markers

MAA Orabi, HMA Khalil, ME Abouelela, D Zaafar… - Pharmaceuticals, 2021 - mdpi.com
Chemotherapeutic-related toxicity exacerbates the increasing death rate among cancer
patients, necessitating greater efforts to find a speedy solution. An in vivo assessment of the …

[HTML][HTML] The effectiveness of anti-inflammatory agents in reducing chemotherapy-induced cognitive impairment in preclinical models–A systematic review

OJ Haller, I Semendric, RP George… - Neuroscience & …, 2023 - Elsevier
Chemotherapy-induced cognitive impairment (CICI) is a debilitating condition resulting from
chemotherapy administration for cancer treatment. CICI is characterised by various cognitive …

Basic approach on the protective effects of hesperidin and naringin in Alzheimer's disease

M Kuşi, E Becer, HS Vatansever - Nutritional Neuroscience, 2024 - Taylor & Francis
Objectives Alzheimer's disease (AD) is a neurodegenerative disease characterized by
cognitive impairment. This situation imposes a great burden on individuals, both …

Role of bone marrow mesenchymal stem cell-derived exosomes in reducing neurotoxicity and depression-like behaviors induced by doxorubicin in rats

DRI Abdel-Gawad, F Khalil, O Shehata… - Toxicology …, 2024 - academic.oup.com
Background Doxorubicin (DOX) is a broad-spectrum antitumor drug while its use is limited
nowadays due to its neurobiological side effects associated with depression. Bone marrow …

[PDF][PDF] Prophylactic and ameliorative effect of N-acetylcysteine on doxorubicin-induced neurotoxicity in Wister rats

WI Mohammed, RA Radwan… - Egyptian Journal of …, 2019 - pdfs.semanticscholar.org
Doxorubicin (DOX) is an anthracycline antibiotic and a quinone-containing
chemotherapeutic drug used for various types of cancers. However, as with most anticancer …

GABA Administration Ameliorates the Toxicity of Doxorubicin on CSF and the Brain of Albino Rats

HM Abdelsalam - Annals of Neurosciences, 2024 - journals.sagepub.com
Background Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the
mammalian brain and is a non-proteinogenic amino acid. Doxorubcin (DOX) or adriamycin …