Onchocerciasis-associated epilepsy: an update and future perspectives

A Hadermann, LJ Amaral, G Van Cutsem… - Trends in …, 2023 - cell.com
Onchocerciasis-associated epilepsy (OAE) is an important neglected public health problem
in areas with high ongoing onchocerciasis transmission. The risk that children in such areas …

[HTML][HTML] Case definitions for onchocerciasis-associated epilepsy and nodding syndrome: A focused review

G Van Cutsem, JNS Fodjo, MCJ Dekker… - … : European Journal of …, 2023 - Elsevier
Onchocerciasis-associated epilepsy (OAE) is an important but neglected public health
problem in onchocerciasis-endemic areas with insufficient or inadequate onchocerciasis …

Effect of onchocerciasis elimination measures on the incidence of epilepsy in Maridi, South Sudan: a 3-year longitudinal, prospective, population-based study

SR Jada, LJ Amaral, T Lakwo, JY Carter… - The Lancet Global …, 2023 - thelancet.com
Background High onchocerciasis transmission predisposes endemic communities to a high
epilepsy burden. The 4· 4% epilepsy prevalence documented in 2018 in Maridi, South …

Impact of a bi-annual community-directed treatment with ivermectin programme on the incidence of epilepsy in an onchocerciasis-endemic area of Mahenge …

D Bhwana, LJ Amaral, A Mhina… - PLoS neglected …, 2023 - journals.plos.org
Background Community-directed treatment with ivermectin (CDTi) is used to eliminate
onchocerciasis. However, despite 25 years of annual CDTi in Mahenge, Tanzania, the …

Systematic and state-of the science review of the role of environmental factors in Amyotrophic Lateral Sclerosis (ALS) or Lou Gehrig's Disease

ME Newell, S Adhikari, RU Halden - Science of The Total Environment, 2022 - Elsevier
The etiology of sporadic amyotrophic lateral sclerosis (ALS) is still unclear. We evaluate
environmental factors suspected to be associated with ALS for their potential linkage to …

[HTML][HTML] Mapping, associated factors, and pathophysiology of nodding syndrome in Africa: A systematic review

S Metanmo, D Dossa, DN Ahmat, AS Winkler… - …, 2024 - karger.com
Introduction: Nodding syndrome (NS) remains a poorly understood disorder. For a long time,
it has been thought to be restricted to East Africa; however, cases in Central Africa have …

Modelling onchocerciasis-associated epilepsy and the impact of ivermectin treatment on its prevalence and incidence

JN Stapley, JID Hamley, M Walker, MA Dixon… - Nature …, 2024 - nature.com
Retrospective cohort studies in Cameroon found an association between Onchocerca
volvulus microfilarial load in childhood (measured in 1991–1993) and risk of developing …

The prevalence of onchocerciasis-associated epilepsy in Mundri West and East Counties, South Sudan: A door-to-door survey

SR Jada, A Dusabimana, G Abd-Elfarag, S Okaro… - Pathogens, 2022 - mdpi.com
A two-phase survey of epilepsy was conducted in selected villages in Mundri West and East
Counties (26 June–8 July, 2021), an onchocerciasis-endemic area in Western Equatoria …

Nodding syndrome, a case-control study in Mahenge, Tanzania: Onchocerca volvulus and not Mansonella perstans as a risk factor

LJ Amaral, D Bhwana, AD Mhina… - PLoS neglected …, 2023 - journals.plos.org
Background Nodding syndrome (NS) has been consistently associated with onchocerciasis.
Nevertheless, a positive association between NS and a Mansonella perstans infection was …

High prevalence of Epilepsy in an onchocerciasis-endemic area in Mvolo County, South Sudan: a Door-To-Door survey

S Raimon, A Dusabimana, G Abd-Elfarag, S Okaro… - Pathogens, 2021 - mdpi.com
In June 2020, a door-to-door household survey was conducted in Mvolo County, an
onchocerciasis-endemic area in South Sudan. A total of 2357 households containing 15,699 …