Recent discoveries on marine organism immunomodulatory activities

E Montuori, D de Pascale, C Lauritano - Marine Drugs, 2022 - mdpi.com
Marine organisms have been shown to be a valuable source for biologically active
compounds for the prevention and treatment of cancer, inflammation, immune system …

Teleost cytotoxic T cells

T Yamaguchi, F Takizawa, M Furihata… - Fish & shellfish …, 2019 - Elsevier
Cell-mediated cytotoxicity is one of the major mechanisms by which vertebrates control
intracellular pathogens. Two cell types are the main players in this immune response …

Exploring small cationic peptides of different origin as potential antimicrobial agents in aquaculture

R León, M Ruiz, Y Valero, C Cárdenas… - Fish & Shellfish …, 2020 - Elsevier
Antimicrobial peptides (AMPs) form part of the innate immune response, which is of vital
importance in fish, especially in eggs and early larval stages. Compared to antibiotics, AMPs …

In vitro immunomodulatory activities of peptides derived from Salmo salar NK-lysin and cathelicidin in fish cells

J Acosta, F Roa, I González-Chavarría, A Astuya… - Fish & shellfish …, 2019 - Elsevier
Antimicrobial peptides (AMPs) are amphipathic peptides, which play an important role in
innate defence. These peptides are gene-encoded and either constitutively expressed …

Antimicrobial activity and mechanisms of a derived antimicrobial peptide TroNKL-27 from golden pompano (Trachinotus ovatus) NK-lysin

H Zhang, Z Cao, Q Diao, Y Zhou, J Ao, C Liu… - Fish & Shellfish …, 2022 - Elsevier
NK-lysin, a homologue of granulysin among human, is predominantly found in natural killer
cells and cytotoxic T-lymphocytes, which plays a pivotal part in innate immune responses …

Molecular characterization of the NK-lysin in a teleost fish, Boleophthalmus pectinirostris: Antimicrobial activity and immunomodulatory activity on monocytes …

FF Ding, CH Li, J Chen - Fish & Shellfish Immunology, 2019 - Elsevier
NK-lysin (NKL) is a cationic host defense peptide that plays an important role in host
immune responses against various pathogens. However, the immunomodulatory activity of …

NKHs27, a sevenband grouper NK-Lysin peptide that possesses immunoregulatory and antimicrobial activity

C Wang, X Yan, G Wang, W Liu, Y Wang, D Hao… - Fish & Shellfish …, 2023 - Elsevier
As an effective and broad-spectrum antimicrobial peptide, NK-Lysin is attracted more and
more attention at present. However, the functions and action mechanism of NK-Lysin …

Antimicrobial and immunoregulatory activities of the derived peptide of a natural killer lysin from black rockfish (Sebastes schlegelii)

D Hao, G Wang, N Li, H Liu, C Wang, W Liu… - Fish & Shellfish …, 2022 - Elsevier
Natural killer lysin (NK-lysin) is a small molecule antimicrobial peptide secreted by natural
killer cells and T lymphocytes. In this study, we characterized a cDNA sequence encoding …

Turbot (Scophthalmus maximus) Nk-lysin induces protection against the pathogenic parasite Philasterides dicentrarchi via membrane disruption

R Lama, P Pereiro, MM Costa, JA Encinar… - Fish & shellfish …, 2018 - Elsevier
P. dicentrarchi is one of the most threatening pathogens for turbot aquaculture. This
protozoan ciliate is a causative agent of scuticociliatosis, which is a disease with important …

Fish galectin8-like exerts positive regulation on immune response against bacterial infection

J Niu, Y Huang, X Liu, F Wu, J Tang, B Wang… - Frontiers in …, 2020 - frontiersin.org
Galectin-8 is a member of the galectin family that is involved in immune response against
pathogens. However, the roles of fish galectin-8 during pathogen infection require …