Therapeutic implications of caffeic acid in cancer and neurological diseases

M Alam, S Ahmed, AM Elasbali, M Adnan… - Frontiers in …, 2022 - frontiersin.org
Caffeic acid (CA) is found abundantly in fruits, vegetables, tea, coffee, oils, and more. CA
and its derivatives have been used for many centuries due to their natural healing and …

[HTML][HTML] Caffeine effects on systemic metabolism, oxidative-inflammatory pathways, and exercise performance

RP Barcelos, FD Lima, NR Carvalho, G Bresciani… - Nutrition Research, 2020 - Elsevier
Caffeine, a xanthine alkaloid compound, is consumed widely and daily by humans, as it is
present in several regular beverages such as tea, coffee, soda beverages, and some drugs …

Possible effects and mechanisms of dietary natural products and nutrients on depression and anxiety: A narrative review

SX Wu, J Li, DD Zhou, RG Xiong, SY Huang, A Saimaiti… - Antioxidants, 2022 - mdpi.com
Depression and anxiety are severe public health problems and have attracted more and
more attention from researchers of food science and nutrition. Dietary natural products and …

Astrocytic MicroRNAs and transcription factors in Alzheimer's disease and therapeutic interventions

A Nassar, T Kodi, S Satarker, P Chowdari Gurram… - Cells, 2022 - mdpi.com
Astrocytes are important for maintaining cholesterol metabolism, glutamate uptake, and
neurotransmission. Indeed, inflammatory processes and neurodegeneration contribute to …

Caffeic acid, a dietary polyphenol, as a promising candidate for combination therapy

S Maity, M Kinra, M Nampoothiri, D Arora, KSR Pai… - Chemical Papers, 2022 - Springer
Increased effectiveness and decreasing toxicity are prime objectives in drug research.
Overwhelming evidence suggests the use of appropriate combination therapy for the better …

Thigmotaxis in a virtual human open field test

D Gromer, DP Kiser, P Pauli - Scientific Reports, 2021 - nature.com
Animal models are used to study neurobiological mechanisms in mental disorders. Although
there has been significant progress in the understanding of neurobiological underpinnings …

Involvement of indoleamine 2, 3-dioxygenase (IDO) and brain-derived neurotrophic factor (BDNF) in the neuroprotective mechanisms of ferulic acid against …

SB Mallik, J Mudgal, M Kinra, S Hall, GD Grant… - Metabolic Brain …, 2023 - Springer
Objective: Ferulic acid (FA) is a common food ingredient that is abundantly present in
various routinely consumed food and beverages. Like many cinnamic acid derivatives, FA …

Repressor element-1 binding transcription factor (REST) as a possible epigenetic regulator of neurodegeneration and MicroRNA-based therapeutic strategies

A Nassar, S Satarker, PC Gurram, D Upadhya… - Molecular …, 2023 - Springer
Neurodegenerative disorders (NDD) have grabbed significant scientific consideration due to
their fast increase in prevalence worldwide. The specific pathophysiology of the disease and …

Remedial effects of caffeine against depressive-like behaviour in mice by modulation of neuroinflammation and BDNF

S Basu Mallik, J Mudgal, S Hall, M Kinra… - Nutritional …, 2022 - Taylor & Francis
Objective: Caffeine (CAF) is one of the most commonly consumed nutritional stimulant in
beverages. Interestingly, CAF produces varied effects in a dose-dependent manner, and that …

Comparable benefits of stingless bee honey and Caffeic acid in mitigating the negative effects of metabolic syndrome on the brain

NN Muhammad Abdul Kadar, F Ahmad, SL Teoh… - Antioxidants, 2022 - mdpi.com
There is mounting evidence that metabolic syndrome (MetS) contributes to the development
of neurodegenerative disorders such as Alzheimer's disease. Honey, which has been used …