RNA-binding proteins (RBPs) comprise a large class of over 2,000 proteins that interact with
transcripts in all manner of RNA-driven processes. The structures and mechanisms that …

Hfq is a ubiquitous, Sm‐like RNA binding protein found in most bacteria and some archaea.
Hfq binds small regulatory RNAs (sRNAs), facilitates base pairing between sRNAs and their …

The structure, function and reactions of nucleic acids are central to molecular biology and
are crucial for the understanding of complex biological processes involved. Revised and …

The origin story and emergence of molecular biology is muddled. The early triumphs in
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …

The conserved RNA‐binding protein Hfq, originally discovered in Escherichia coli as a host
factor for Qβ replicase, has emerged as a pleiotropic regulator that modulates the stability or …

Recent studies on Hfq have provided a deeper understanding of the multiple functions of
this pleiotropic post-transcriptional regulator. Insights into the mechanism of Hfq action have …

In the yeast Saccharomyces cerevisiae, distinct regions of the 1.2-kb telomerase RNA
(TLC1) bind to the catalytic subunit Est2p and to accessory proteins. In particular, a bulged …

The Hfq protein was discovered in Escherichia coli in the early seventies as a host factor for
the Qβ phage RNA replication. During the last decade, it was shown to be involved in many …

The bacterial Sm-like protein Hfq facilitates RNA-RNA interactions involved in post-
transcriptional regulation of the stress response. Specifically, Hfq helps pair noncoding …

Cytokinesis completes cell division and partitions the contents of one cell to the two
daughter cells. Here we characterize CAR-1, a predicted RNA binding protein that is …