Patient selection for CAR T or BiTE therapy in multiple myeloma: Which treatment for each patient?

D Kegyes, C Constantinescu, L Vrancken… - Journal of Hematology & …, 2022 - Springer
Multiple myeloma (MM) is a plasma cell malignancy that affects an increasing number of
patients worldwide. Despite all the efforts to understand its pathogenesis and develop new …

Bone disease in multiple myeloma: biologic and clinical implications

ZS Bernstein, EB Kim, N Raje - Cells, 2022 - mdpi.com
Multiple Myeloma (MM) is a hematologic malignancy characterized by the proliferation of
monoclonal plasma cells localized within the bone marrow. Bone disease with associated …

The epidemiological landscape of multiple myeloma: a global cancer registry estimate of disease burden, risk factors, and temporal trends

J Huang, SC Chan, V Lok, L Zhang… - The Lancet …, 2022 - thelancet.com
Background Multiple myeloma accounted for 176 404 (14%) of 1 278 362 the incidence
cases leukaemia, lymphoma, and multiple myeloma in 2020. Identifying its geographical …

Leukocyte immunoglobulin-like receptor B1 (LILRB1) protects human multiple myeloma cells from ferroptosis by maintaining cholesterol homeostasis

M Xian, Q Wang, L Xiao, L Zhong, W Xiong, L Ye… - Nature …, 2024 - nature.com
Multiple myeloma (MM) is a hematologic malignancy characterized by uncontrolled
proliferation of plasma cells in the bone marrow. MM patients with aggressive progression …

Immunotherapy of multiple myeloma: current status as prologue to the future

HN Abramson - International Journal of Molecular Sciences, 2023 - mdpi.com
The landscape of therapeutic measures to treat multiple myeloma has undergone a seismic
shift since the dawn of the current century. This has been driven largely by the introduction of …

Multiple myeloma incidence and mortality trends in the United States, 1999–2020

DT Zhu, A Park, A Lai, L Zhang, H Attar… - Scientific Reports, 2024 - nature.com
Multiple myeloma (MM) is a plasma cell disorder accounting for approximately 10% of
hematologic malignancies. There is limited epidemiological evidence regarding the long …

Bispecific antibodies for the management of relapsed/refractory multiple myeloma

P Tacchetti, S Barbato, K Mancuso, E Zamagni, M Cavo - Cancers, 2024 - mdpi.com
Simple Summary Bispecific antibodies (BsAbs) provide a new mode of targeting multiple
myeloma (MM) plasma cells (PCs), basing their action on the activation and redirection of …

Metabolomic biomarkers of multiple myeloma: A systematiс review

VG Varzieva, NV Mesonzhnik, IS Ilgisonis… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Multiple myeloma is an incurable malignancy of clonal plasma cells. Various diagnostic
methods are used in parallel to accurately determine stage and severity of the disease …

[HTML][HTML] Communication between bone marrow mesenchymal stem cells and multiple myeloma cells: Impact on disease progression

D García-Sánchez, A González-González… - World Journal of Stem …, 2023 - ncbi.nlm.nih.gov
Multiple myeloma (MM) is a hematological malignancy characterized by the accumulation of
immunoglobulin-secreting clonal plasma cells at the bone marrow (BM). The interaction …

Autologous stem cell transplantation in multiple myeloma: where are we and where do we want to go?

S Morè, L Corvatta, VM Manieri, F Saraceni… - Cells, 2022 - mdpi.com
The introduction of high-dose therapy in the 1990s as well as the development of drugs such
as thalidomide, lenalidomide, and bortezomib in the 2000s led to an impressive …