Humans are exposed to nanoscopical nanobiovectors (eg coronavirus SARS-CoV-2) as
well as abiotic metal/carbon-based nanomaterials that enter cells serendipitously or …

Nanoparticles (NP) are attractive options for the therapeutic delivery of active
pharmaceutical drugs, proteins and nucleic acids into cells, tissues and organs. Research …

Introduction Patients with relapsed or refractory multiple myeloma (RRMM) represent an
unmet clinical need. Belantamab mafodotin (belamaf; GSK2857916) is a first-in-class …

The recent remarkable success and safety of mRNA lipid nanoparticle technology for
producing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines has …

Abstract Nanocrystals have contributed to exciting improvements in the delivery of poorly
water-soluble drugs. The biological and intracellular fates of nanocrystals are currently …

Sufficient ocular bioavailability is often considered a challenge by the researchers, due to
the complex structure of the eye and its protective physiological mechanisms. In addition, the …

Intravesical chemotherapy is generally used in the clinic for treating bladder cancer (BCa),
but its efficacy is limited due to the permeation barrier and side effects caused by the off …

The aim of this study was to evaluate the uptake mechanism of thiolated nanostructured lipid
carriers (NLCs). NLCs were decorated with a short-chain polyoxyethylene (10) stearyl ether …

Rationale: Malignant ascites caused by cancer cells results in poor prognosis and short
average survival time. No effective treatment is currently available for malignant ascites. In …

Glaucoma is a group of diseases characterized by progressive degeneration of retinal
ganglion cells, leading to irreversible blindness. Currently, intraocular pressure reduction is …