Abstract Glycogen synthase kinase-3 (GSK3) may be the busiest kinase in most cells, with
over 100 known substrates to deal with. How does GSK3 maintain control to selectively …

Synaptic plasticity confers environmental adaptability through modification of the
connectivity between neurons and neuronal circuits. This is achieved through changes to …

Summary Glycogen synthase kinase-3 (GSK3) has been implicated in major neurological
disorders, but its role in normal neuronal function is largely unknown. Here we show that …

Aggregation of hyperphosphorylated tau is one of the characteristic neuropathological
lesions of Alzheimer's disease and other neurodegenerative disorders. Pharmacological …

Both thymoquinone (TQ) and thymol (T) have been proved to possess a positive impact on
human health. In this research, we aimed to investigate the effect of these compounds …

Glycogen synthase kinase‐3 (GSK‐3), an important component of the glycogen metabolism
pathway, is highly expressed in the CNS. It has been implicated in major neurological …

The physiological importance of GSK3-like kinases in plants emerged when the functional
role of plant GSK3-like kinases represented by BIN2 was first elucidated in the …

Glycogen synthase kinase-3 (GSK-3) has many cellular functions. Recent evidence
suggests that it plays a key role in certain types of synaptic plasticity, in particular a form of …

Glycogen synthase kinase-3 (GSK-3) is a ubiquitously expressed serine/threonine kinase
that is particularly abundant in the CNS. Dysregulation of GSK-3 activity is believed to play a …

The mood stabilizer lithium inhibits glycogen synthase kinase-3 (GSK-3) directly or indirectly
by enhancing serine phosphorylation of both α and β isoforms. Lithium robustly protected …