A guide to the expanding field of extracellular vesicles and their release in regulated cell death programs

B Cappe, P Vandenabeele, FB Riquet - The FEBS Journal, 2024 - Wiley Online Library
Homeostasis disruption is visible at the molecular and cellular levels and may often lead to
cell death. This vital process allows us to maintain the more extensive system's integrity by …

[HTML][HTML] Recent Advances of Small Extracellular Vesicles for the Regulation and Function of Cancer-Associated Fibroblasts

C Liang, M Wang, Y Huang, JWP Yam… - International Journal of …, 2024 - mdpi.com
Cancer-associated fibroblasts (CAFs) are a heterogeneous cell population in the tumor
microenvironment (TME) that critically affect cancer progression. Small extracellular vesicles …

[HTML][HTML] The paracaspase MALT1 controls cholesterol homeostasis in glioblastoma stem-like cells through lysosome proteome shaping

C Maghe, K Trillet, G André-Grégoire, M Kerhervé… - Cell Reports, 2024 - cell.com
Glioblastoma stem-like cells (GSCs) compose a tumor-initiating and-propagating population
remarkably vulnerable to variation in the stability and integrity of the lysosomal compartment …

[HTML][HTML] Isolating plasma extracellular vesicles from mouse blood using size-exclusion chromatography, density gradient, and ultracentrifugation

G André-Grégoire, Q Roux, J Gavard - STAR protocols, 2023 - Elsevier
Circulating extracellular vesicles (EVs) could serve for the surveillance of diverse
pathological conditions. We present a protocol for enriching and isolating plasma EVs from …

Dysregulation of intercellular communication in vitro and in vivo via extracellular vesicles secreted by pancreatic duct adenocarcinoma cells and generated under the …

L Nannan, S Decombis, C Terryn… - Journal of …, 2024 - Wiley Online Library
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy with poor
prognosis due to its highly metastatic profile. Intercellular communication between cancer …

Necrosulfonamide causes oxidation of PCM1 and impairs ciliogenesis and autophagy

CCN Renaud, CA Nicolau, C Maghe, K Trillet… - Iscience, 2024 - cell.com
Centriolar satellites are high-order assemblies, scaffolded by the protein PCM1, that
gravitate as particles around the centrosome and play pivotal roles in fundamental cellular …

[HTML][HTML] MLKL et les reliques de la mort

G André-Grégoire, J Gavard - médecine/sciences, 2023 - medecinesciences.org
Le glioblastome est une tumeur primaire du système nerveux central. Il est l'un des cancers
de l'adulte les plus graves, avec une survie médiane de 15 mois. L'échec des thérapies …