The majority of anticancer agents has in common DNA-damaging properties and affects not
only target-cells but also non-tumour cells. Its genotoxicity has been demonstrated in …

Many antineoplastic drugs used to treat cancer, particularly alkylating agents and
topoisomerase inhibitors, are known to induce genetic damage in patients. Elevated levels …

Objective: To determine the frequency of “signature” chromosomal abnormalities in
oncology workers handling anticancer drugs. Methods: Peripheral blood from health care …

Background To determine the relationships of potential occupational exposure to
antineoplastic drugs with cancer incidence and adverse pregnancy outcomes in a historical …

Objectives: Antineoplastic drugs are widely used in anticancer therapy due to their cytotoxic
activity but many of them are classified as carcinogenic, mutagenic, or teratogenic to …

Objectives Exposure to antineoplastic drugs should be avoided due to the risk of getting
adverse health effects. Antineoplastic drugs such as cyclophosphamide (CP) and ifosfamide …

A large-scale study was carried out in order to determine the contamination level of
antineoplastic drugs in pharmacies and to investigate the suitability and effects of wipe …

Purpose Many antineoplastic drugs are classified as carcinogenic, mutagenic and
teratogenic for humans. Therefore, minimization of exposure is required to reduce health …

Exposure assessment of health care workers to antineoplastic drugs (ADs) is still an open
issue since new, critical, and emerging factors may put pharmacists who prepare hazardous …

The use of antineoplastic agents for the treatment of cancer and other non-neoplastic
diseases is an increasingly common practice in hospitals. As a result, workers involved with …