Spatial analyses of immune cell infiltration in cancer: current methods and future directions: A report of the International Immuno‐Oncology Biomarker Working Group …

DB Page, G Broeckx, CA Jahangir… - The Journal of …, 2023 - Wiley Online Library
Modern histologic imaging platforms coupled with machine learning methods have provided
new opportunities to map the spatial distribution of immune cells in the tumor …

Early Breast Cancer Risk Assessment: Integrating Histopathology with Artificial Intelligence

M Ivanova, C Pescia, D Trapani, K Venetis… - Cancers, 2024 - mdpi.com
Simple Summary Risk assessment in early breast cancer is critical for clinical decisions, but
defining risk categories poses a significant challenge. The integration of conventional …

[HTML][HTML] Artificial intelligence in breast cancer diagnosis and treatment: advances in imaging, pathology, and personalized care

P Uchikov, U Khalid, GH Dedaj-Salad, D Ghale… - Life, 2024 - mdpi.com
Breast cancer is the most prevalent cancer worldwide, affecting both low-and middle-income
countries, with a growing number of cases. In 2024, about 310,720 women in the US are …

Artificial intelligence in digital histopathology for predicting patient prognosis and treatment efficacy in breast cancer

C McCaffrey, C Jahangir, C Murphy… - Expert Review of …, 2024 - Taylor & Francis
Introduction Histological images contain phenotypic information predictive of patient
outcomes. Due to the heavy workload of pathologists, the time-consuming nature of …

Exploring Biomarkers in Breast Cancer: Hallmarks of Diagnosis, Treatment, and Follow-Up in Clinical Practice

L Lopez-Gonzalez, A Sanchez Cendra… - Medicina, 2024 - mdpi.com
Breast cancer is a prevalent malignancy in the present day, particularly affecting women as
one of the most common forms of cancer. A significant portion of patients initially present …

Differential immunomodulatory effects of epirubicin/cyclophosphamide and docetaxel in breast cancer patients

K Wimmer, M Sachet, C Ramos, S Frantal… - Journal of Experimental …, 2023 - Springer
Background Epirubicin/cyclophosphamide (EC) and docetaxel (D) are commonly used in a
sequential regimen in the neoadjuvant treatment of early, high-risk or locally advanced …

[HTML][HTML] Tumor-Infiltrating Lymphocyte Scoring in Neoadjuvant-Treated Breast Cancer

N Thomas, S Garaud, M Langouo, D Sofronii… - Cancers, 2024 - mdpi.com
Simple Summary TIL scoring has been recommended as a biomarker in routine clinical
practice in breast cancer patients. Currently, the standard of care for early breast cancer is …

A Deep Learning–Based Assessment Pipeline for Intraepithelial and Stromal Tumor-Infiltrating Lymphocytes in High-Grade Serous Ovarian Carcinoma

K Hamada, R Murakami, A Ueda, Y Kashima… - The American Journal of …, 2024 - Elsevier
Tumor-infiltrating lymphocytes (TILs) are associated with improved survival in patients with
epithelial ovarian cancer. However, the evaluation of TILs has not been applied to routine …

An interpretable framework for inter-observer agreement measurements in TILs scoring on histopathological breast images: A proof-of-principle study

A Capar, DA Ekinci, M Ertano, MKK Niazi, EB Balaban… - PloS one, 2024 - journals.plos.org
Breast cancer, a widespread and life-threatening disease, necessitates precise diagnostic
tools for improved patient outcomes. Tumor-Infiltrating Lymphocytes (TILs), reflective of the …

[HTML][HTML] Tumor infiltrating lymphocytes (TILs)–Pathologia, quo vadis?–A global survey

K Skok, K Bräutigam - Pathology-Research and Practice, 2025 - Elsevier
Tumor-infiltrating lymphocytes (TILs) and the tumor microenvironment have become
increasingly important in cancer research, and immunotherapy has achieved major …