[HTML][HTML] Human viral oncogenesis: a cancer hallmarks analysis

EA Mesri, MA Feitelson, K Munger - Cell host & microbe, 2014 - cell.com
Approximately 12% of all human cancers are caused by oncoviruses. Human viral
oncogenesis is complex, and only a small percentage of the infected individuals develop …

Kaposi's sarcoma and its associated herpesvirus

EA Mesri, E Cesarman, C Boshoff - Nature Reviews Cancer, 2010 - nature.com
Kaposi's sarcoma (KS) is the most common cancer in HIV-infected untreated individuals.
Kaposi's sarcoma-associated herpesvirus (KSHV; also known as human herpesvirus 8 …

[HTML][HTML] KSHV and the pathogenesis of Kaposi sarcoma: listening to human biology and medicine

D Ganem - The Journal of clinical investigation, 2010 - Am Soc Clin Investig
The linkage of Kaposi sarcoma (KS) to infection by a novel human herpesvirus (Kaposi
sarcoma–associated herpesvirus [KSHV]) is one of the great successes of contemporary …

[HTML][HTML] Viral control of mitochondrial apoptosis

L Galluzzi, C Brenner, E Morselli, Z Touat… - PLoS …, 2008 - journals.plos.org
Throughout the process of pathogen–host co-evolution, viruses have developed a battery of
distinct strategies to overcome biochemical and immunological defenses of the host. Thus …

Kaposi sarcoma herpesvirus pathogenesis

G Mariggio, S Koch, TF Schulz - … Transactions of the …, 2017 - royalsocietypublishing.org
Kaposi sarcoma herpesvirus (KSHV), taxonomical name human gammaherpesvirus 8, is a
phylogenetically old human virus that co-evolved with human populations, but is now only …

[HTML][HTML] G-quadruplexes: more than just a kink in microbial genomes

N Saranathan, P Vivekanandan - Trends in microbiology, 2019 - cell.com
G-quadruplexes (G4s) are noncanonical nucleic acid secondary structures formed by
guanine-rich DNA and RNA sequences. In this review we aim to provide an overview of the …

KSHV: pathways to tumorigenesis and persistent infection

L Giffin, B Damania - Advances in virus research, 2014 - Elsevier
Kaposi's sarcoma-associated herpesvirus (KSHV; also known as human herpesvirus 8) is
the etiologic agent of Kaposi's sarcoma, primary effusion lymphoma, and multicentric …

Expression of the Epstein-Barr virus-encoded Epstein-Barr virus nuclear antigen 1 in Hodgkin's lymphoma cells mediates Up-regulation of CCL20 and the migration of …

KRN Baumforth, A Birgersdotter, GM Reynolds… - The American journal of …, 2008 - Elsevier
In∼ 50% of patients with Hodgkin's lymphoma (HL), the Epstein-Barr virus (EBV), an
oncogenic herpesvirus, is present in tumor cells. After microarray profiling of both HL tumors …

[HTML][HTML] Molecular biology of KSHV lytic reactivation

P Purushothaman, T Uppal, SC Verma - Viruses, 2015 - mdpi.com
Kaposi's sarcoma-associated herpesvirus (KSHV) primarily persists as a latent episome in
infected cells. During latent infection, only a limited number of viral genes are expressed that …

Kaposi Sarcoma-associated Herpesvirus: mechanisms of oncogenesis

TF Schulz, E Cesarman - Current opinion in virology, 2015 - Elsevier
Highlights•KSHV/HHV8 causes three human diseases: Kaposi Sarcoma, Primary Effusion
Lymphoma and the plasma cell variant of Multicentric Castleman Disease.•These occur …