Protein synthesis is a tightly regulated process that enables post-transcriptional control of
gene expression. Dysregulation of this process is associated with the development and …

Cancer is one of the most studied areas of human biology over the past century. Despite
having attracted much attention, hype, and investments, the search to find a cure for cancer …

Protein synthesis and its regulatory signaling pathways play essential roles in the initiation
and maintenance of the cancer phenotype. Insight obtained over the last 3 decades on the …

Protein synthesis is an essential cellular process that is highly responsive to extra-and
intracellular cues such as mitogens, growth signals, nutrient and energy status, and stress …

The transition-metal-catalyzed synthesis of spiroketals is a rapidly growing area and these
methods have facilitated the use of new spiroketal synthons as latent spiroketal equivalents …

It is reported that Hg (ClO4) 2· 3H2O could efficiently activate the cheap but less reactive
allyltrimethylsilane for the allylation of isatins or isatin ketoimines, with catalyst loading down …

A defining feature of many cancers is deregulated translational control. Typically, this occurs
at the level of recruitment of the 40S ribosomes to the 5′-cap of cellular messenger RNAs …

A unified and protecting-group-free six-step total synthesis of bisabolane-type
sesquiterpenoid beshanzuenone D and its stereoisomers and abiespiroside A using S-(+) …

A novel Lewis acid catalyzed intermolecular cascade annulation of alkynols with α-
ketoesters has been developed. This simple and efficient cascade annulation proceeds …

Inhibiting eukaryotic protein translation with small molecules is emerging as a powerful
therapeutic strategy. The advantage of targeting cellular translational machinery is that it is …