Summary The 2015 Magnetic Resonance Imaging in Multiple Sclerosis and 2016
Consortium of Multiple Sclerosis Centres guidelines on the use of MRI in diagnosis and …

MRI has improved the diagnostic work-up of multiple sclerosis, but inappropriate image
interpretation and application of MRI diagnostic criteria contribute to misdiagnosis. Some …

Multiple sclerosis (MS) is a neuroinflammatory disease with a relapsing–remitting disease
course at early stages, distinct lesion characteristics in cortical grey versus subcortical white …

During the past decades, better understanding of relapsing-remitting multiple sclerosis
disease mechanisms have led to the development of several disease-modifying therapies …

Importance Cognitive impairment is a common and disabling feature of multiple sclerosis
(MS), but a precise characterization of cognitive phenotypes in patients with MS is lacking …

Pathological evaluation is the gold standard for identifying processes related to multiple
sclerosis that explain disease manifestations, and for guiding the development of new …

Growing evidence from cerebrospinal fluid samples and post-mortem brain tissue from
individuals with multiple sclerosis (MS) and rodent models indicates that the meninges have …

In multiple sclerosis, spontaneous remyelination is generally incomplete and heterogeneous
across patients. A high heterogeneity in remyelination may also exist across lesions within …

Neuroaxonal pathology is a main determinant of disease progression in multiple sclerosis;
however, its underlying pathophysiological mechanisms, including its link to inflammatory …

This review discusses the major contributors to the subtle magnetic properties of brain tissue
and how they affect MRI contrast. With the increased availability of high‐field scanners, the …