[HTML][HTML] Anti-inflammatory and immunoregulatory effects of paeoniflorin and total glucosides of paeony

L Zhang, W Wei - Pharmacology & therapeutics, 2020 - Elsevier
Abstract As a Traditional Chinese Medicine, Paeonia lactiflora Pallas has been used to treat
pain, inflammation and immune disorders for more than 1000 years in China. Total …

Role of natural products in alleviation of rheumatoid arthritis—A review

D Sharma, P Chaubey… - Journal of food …, 2021 - Wiley Online Library
Rheumatoid arthritis (RHA) is one of the most prevalent complex, chronic, inflammatory
diseases, manifested by elevated oxidative stress and inflammatory biomarkers. Prolonged …

Stigmasterol protects rats from collagen induced arthritis by inhibiting proinflammatory cytokines

MA Khan, AHMG Sarwar, R Rahat, RS Ahmed… - International …, 2020 - Elsevier
Rheumatoid arthritis (RA) is an autoimmune disorder, in which imbalance in synthesis and
production of inflammatory cytokines promotes cartilage and bone destruction. Out of the …

Curcumin induces apoptosis and cell cycle arrest via the activation of reactive oxygen species–independent mitochondrial apoptotic pathway in Smad4 and p53 …

A Agarwal, A Kasinathan, R Ganesan… - Nutrition Research, 2018 - Elsevier
Curcumin is a natural dietary polyphenol compound that has various pharmacological
activities such as antiproliferative and cancer-preventive activities on tumor cells. Indeed, the …

Interleukin 17 regulates SHP-2 and IL-17RA/STAT-3 dependent Cyr61, IL-23 and GM-CSF expression and RANKL mediated osteoclastogenesis by fibroblast-like …

R Ganesan, M Rasool - Molecular immunology, 2017 - Elsevier
Abstract Interleukin (IL)-17 predominately produced by the Th17 cells, plays a crucial role in
the fibroblast-like synoviocytes (FLS) mediated disease process of rheumatoid arthritis (RA) …

Long noncoding RNA MEG3 regulates rheumatoid arthritis by targeting NLRC5

Y Liu, L Yang, Q Xu, XY Lu, TT Ma… - Journal of cellular …, 2019 - Wiley Online Library
Rheumatoid arthritis (RA) is one of the chronic systemic autoimmune diseases that
cardinally affect the joints. Many people all over the world suffer from the disease. Fibroblast …

Anti-inflammatory mechanism of geniposide: inhibiting the hyperpermeability of fibroblast-like synoviocytes via the RhoA/p38MAPK/NF-κB/F-actin signal pathway

R Deng, F Li, H Wu, W Wang, L Dai… - Frontiers in …, 2018 - frontiersin.org
Geniposide (GE) is the extraction and purification of iridoid glycosides from the Gardenia
jasminoides Ellis, which is a promising anti-inflammatory drug, but its mechanism of actions …

Anhuienoside C ameliorates collagen-induced arthritis through inhibition of MAPK and NF-κB signaling pathways

Q Liu, XH Xiao, LB Hu, HY Jie, Y Wang… - Frontiers in …, 2017 - frontiersin.org
Anemone flaccida Fr. Schmidt (Ranunculaceae)(Di Wu in Chinese) is used to treat punch
injuries and rheumatoid arthritis (RA). Our previous report has shown that crude triterpenoid …

Ferulic acid inhibits interleukin 17‐dependent expression of nodal pathogenic mediators in fibroblast‐like synoviocytes of rheumatoid arthritis

R Ganesan, M Rasool - Journal of cellular biochemistry, 2019 - Wiley Online Library
Abstract Interleukin 17 (IL‐17), a proinflammatory cytokine produced by T helper (Th) 17
cells, potentially controls fibroblast‐like synoviocytes (FLS)‐mediated disease activity of …

Flemingia philippinensis Flavonoids Relieve Bone Erosion and Inflammatory Mediators in CIA Mice by Downregulating NF‐κB and MAPK Pathways

G Sun, C Xing, L Zeng, Y Huang… - Mediators of …, 2019 - Wiley Online Library
Background. The dry root of Flemingia philippinensis has been widely used in the treatment
of rheumatism, arthropathy, and osteoporosis in traditional Chinese medicine; the …