Intrarenal autoregulatory mechanisms maintain renal blood flow (RBF) and glomerular
filtration rate (GFR) independent of renal perfusion pressure (RPP) over a defined range (80 …

Significance: Renal oxidative stress can be a cause, a consequence, or more often a
potentiating factor for hypertension. Increased reactive oxygen species (ROS) in the kidney …

Objectives: Magnetic resonance elastography (MRE) allows noninvasive assessment of
tissue stiffness in vivo. Renal arterial stenosis (RAS), a narrowing of the renal artery …

Summary NAD (P) H oxidase has been shown to be important in the development of salt-
sensitive hypertension. Here, we show that the expression of a subunit of NAD (P) H …

The physiological evidence linking the production of superoxide, hydrogen peroxide, and
nitric oxide in the renal medullary thick ascending limb of Henle (mTAL) to regulation of …

Increased central venous pressure in congestive heart failure causes renal dysfunction;
however, the underlying mechanisms are unclear. We created a rat renal congestion model …

Salt-sensitive hypertension is associated with renal and vascular dysfunctions, which lead to
impaired fluid excretion, increased cardiac output, and total peripheral resistance. It is …

The frequently occurring condition of renal failure in heart failure (HF) has been termed the
cardiorenal syndrome. However, the importance of renal insufficiency in HF has only been …

Abstract NADPH oxidase 4 (NOX4) is the most abundant NOX isoform in the kidney;
however, its importance for renal function has only recently emerged. The NOX4-dependent …

Congestive heart failure produces fluid volume overload, central and renal venous pressure
elevation, and consequently renal congestion, which results in worsening renal function …