Ischaemia reperfusion injury in liver transplantation: Cellular and molecular mechanisms

WA Dar, E Sullivan, JS Bynon, H Eltzschig… - Liver …, 2019 - Wiley Online Library
Liver disease causing end organ failure is a growing cause of mortality. In most cases, the
only therapy is liver transplantation. However, liver transplantation is a complex undertaking …

[HTML][HTML] Lysophosphatidylcholines modulate immunoregulatory checkpoints in peripheral monocytes and are associated with mortality in people with acute liver …

FM Trovato, R Zia, F Artru, S Mujib, E Jerome… - Journal of …, 2023 - Elsevier
Background & Aims Acute liver failure (ALF) is a life-threatening disease characterised by
high-grade inflammation and immunoparesis, which is associated with a high incidence of …

[HTML][HTML] Recent progress and future direction for the application of multiomics data in clinical liver transplantation

Z Liu, J Xu, S Que, L Geng, L Zhou… - Journal of Clinical …, 2022 - ncbi.nlm.nih.gov
Omics data address key issues in liver transplantation (LT) as the most effective therapeutic
means for end-stage liver disease. The purpose of this study was to review the current …

Liver metabolic dysregulation induced by polypropylene nano-and microplastics in nile tilapia using internal extractive electrospray ionization mass spectrometry

X Wu, M Li, S Yang, J Dong, W Pan, Y Ning… - Analytical …, 2023 - ACS Publications
Understanding the metabolic disorders induced by nano-and microplastics in aquatic
organisms at the molecular level could help us understand the potential toxicity of nano-and …

[PDF][PDF] Alterations in gut microbial function following liver transplant

JS Bajaj, G Kakiyama, IJ Cox, H Nittono… - Liver …, 2018 - Wiley Online Library
Liver transplantation (LT) improves daily function and ameliorates gut microbial composition.
However, the effect of LT on microbial functionality, which can be related to overall patient …

The protective effect of aspirin eugenol ester on paraquat-induced acute liver injury rats

ZD Zhang, YJ Yang, XW Liu, Z Qin, SH Li… - Frontiers in Medicine, 2020 - frontiersin.org
Aspirin eugenol ester (AEE) possesses anti-inflammatory and anti-oxidative effects. The
study was conducted to evaluate the protective effect of AEE on paraquat-induced acute …

Rapid identification of ischemic injury in renal tissue by mass-spectrometry imaging

TC Van Smaalen, SR Ellis, NE Mascini… - Analytical …, 2019 - ACS Publications
The increasing analytical speed of mass-spectrometry imaging (MSI) has led to growing
interest in the medical field. Acute kidney injury is a severe disease with high morbidity and …

Mass spectrometry based metabolomics comparison of liver grafts from donors after circulatory death (DCD) and donors after brain death (DBD) used in human …

O Hrydziuszko, MTPR Perera, R Laing, J Kirwan… - PLoS …, 2016 - journals.plos.org
Use of marginal liver grafts, especially those from donors after circulatory death (DCD), has
been considered as a solution to organ shortage. Inferior outcomes have been attributed to …

A lipidomics study reveals lipid signatures associated with early allograft dysfunction in living donor liver transplantation

HI Tsai, CJ Lo, CW Zheng, CW Lee, WC Lee… - Journal of Clinical …, 2018 - mdpi.com
Liver transplantation has become the ultimate treatment for patients with end stage liver
disease. However, early allograft dysfunction (EAD) has been associated with allograft loss …

Metabolomic and lipidomic landscape of porcine kidney associated with kidney perfusion in heart beating donors and donors after cardiac death

I Stryjak, N Warmuzińska, K Łuczykowski, K Jaroch… - Translational …, 2024 - Elsevier
Transplant centers are currently facing a lack of tools to ensure adequate evaluation of the
quality of the available organs, as well as a significant shortage of kidney donors. Therefore …