Transient receptor potential channels in the vasculature
S Earley, JE Brayden - Physiological reviews, 2015 - journals.physiology.org
The mammalian genome encodes 28 distinct members of the transient receptor potential
(TRP) superfamily of cation channels, which exhibit varying degrees of selectivity for …
(TRP) superfamily of cation channels, which exhibit varying degrees of selectivity for …
KCNQs: ligand-and voltage-gated potassium channels
GW Abbott - Frontiers in physiology, 2020 - frontiersin.org
Voltage-gated potassium (Kv) channels in the KCNQ (Kv7) family are essential features of a
broad range of excitable and non-excitable cell types and are found in organisms ranging …
broad range of excitable and non-excitable cell types and are found in organisms ranging …
Vasorelaxation by hydrogen sulphide involves activation of Kv7 potassium channels
A Martelli, L Testai, MC Breschi, K Lawson… - Pharmacological …, 2013 - Elsevier
Hydrogen sulphide (H2S) has been recently hypothesized to be an endogenous adipocyte-
derived relaxing factor, evoking vasorelaxation of conductance and resistance vessels …
derived relaxing factor, evoking vasorelaxation of conductance and resistance vessels …
Novel treatment strategies for smooth muscle disorders: Targeting Kv7 potassium channels
JM Haick, KL Byron - Pharmacology & therapeutics, 2016 - Elsevier
Smooth muscle cells provide crucial contractile functions in visceral, vascular, and lung
tissues. The contractile state of smooth muscle is largely determined by their electrical …
tissues. The contractile state of smooth muscle is largely determined by their electrical …
Exercise training decreases store-operated Ca2+entry associated with metabolic syndrome and coronary atherosclerosis
JM Edwards, ZP Neeb, MA Alloosh… - Cardiovascular …, 2010 - academic.oup.com
Aims Stenting attenuates restenosis, but accelerated coronary artery disease (CAD)
adjacent to the stent (peri-stent CAD) remains a concern in metabolic syndrome (MetS) …
adjacent to the stent (peri-stent CAD) remains a concern in metabolic syndrome (MetS) …
Differential protein kinase C-dependent modulation of Kv7. 4 and Kv7. 5 subunits of vascular Kv7 channels
LI Brueggemann, AR Mackie, LL Cribbs, J Freda… - Journal of Biological …, 2014 - ASBMB
The Kv7 family (Kv7. 1–7.5) of voltage-activated potassium channels contributes to the
maintenance of resting membrane potential in excitable cells. Previously, we provided …
maintenance of resting membrane potential in excitable cells. Previously, we provided …
Muscling in on TRP channels in vascular smooth muscle cells and cardiomyocytes
L Alonso-Carbajo, M Kecskes, G Jacobs, A Pironet… - Cell Calcium, 2017 - Elsevier
The human TRP protein family comprises a family of 27 cation channels with diverse
permeation and gating properties. The common theme is that they are very important …
permeation and gating properties. The common theme is that they are very important …
MicroRNA‐190 Regulates Hypoxic Pulmonary Vasoconstriction by Targeting a Voltage‐Gated K+ Channel in Arterial Smooth Muscle Cells
SS Li, YJ Ran, DD Zhang, SZ Li… - Journal of cellular …, 2014 - Wiley Online Library
Pulmonary arterial hypertension (PAH) is associated with sustained vasoconstriction,
profound structural remodeling of vasculatures and alterations in Ca2+ homeostasis in …
profound structural remodeling of vasculatures and alterations in Ca2+ homeostasis in …
Large conductance Ca2+‐activated K+ (BK) channels promote secretagogue‐induced transition from spiking to bursting in murine anterior pituitary corticotrophs
Key points Corticotroph cells of the anterior pituitary are electrically excitable and are an
integral component of the hypothalamic‐pituitary‐adrenal axis which governs the …
integral component of the hypothalamic‐pituitary‐adrenal axis which governs the …