Eukaryotic cilia and flagella are evolutionarily conserved organelles that protrude from the
cell surface. The unique location and properties of cilia allow them to function in vital …

The cilium is a complex organelle, the assembly of which requires the coordination of motor-
driven intraflagellar transport (IFT), membrane trafficking and selective import of cilium …

Cilia are ubiquitous eukaryotic organelles impotant for cellular motility, signaling, and
sensory reception. Cilium formation requires intraflagellar transport of structural and …

Eukaryotic cilia and flagella, including primary cilia and sensory cilia, are highly conserved
organelles that project from the surfaces of many cells. The assembly and maintenance of …

Dr. Harris has played a major role in the development of this organism as a model system.
Her previous version of the Chlamydomonas Sourcebook which published in 1989, has …

Intraflagellar transport (IFT) trains are massive molecular machines that traffic proteins
between cilia and the cell body. Each IFT train is a dynamic polymer of two large complexes …

▪ Abstract The unicellular green alga Chlamydomonas offers a simple life cycle, easy
isolation of mutants, and a growing array of tools and techniques for molecular genetic …

Despite the increasing diagnostic rate of genomic sequencing, the genetic basis of more
than 50% of heritable kidney disease remains unresolved. Kidney organoids differentiated …

Intraflagellar transport (IFT) complexes, IFT-A and IFT-B, form bidirectional trains that move
along the axonemal microtubules and are essential for assembling and maintaining cilia …

Primary cilia function as a sensory signaling compartment in processes ranging from
mammalian Hedgehog signaling to neuronal control of obesity. Intraflagellar transport (IFT) …