Liquid biopsy enters the clinic—implementation issues and future challenges

M Ignatiadis, GW Sledge, SS Jeffrey - Nature reviews Clinical oncology, 2021 - nature.com
Historically, studies of disseminated tumour cells in bone marrow and circulating tumour
cells in peripheral blood have provided crucial insights into cancer biology and the …

Liquid biopsies: Potential and challenges

I Heidrich, L Ačkar… - … Journal of Cancer, 2021 - Wiley Online Library
The analysis of tumor cells or tumor cell products obtained from blood or other body fluids
(“liquid biopsy”[LB]) provides a broad range of opportunities in the field of oncology. Clinical …

Comprehensive liquid biopsy analysis as a tool for the early detection of minimal residual disease in breast cancer

D Stergiopoulou, A Markou, A Strati, M Zavridou… - Scientific Reports, 2023 - nature.com
Liquid biopsy (LB) provides a unique minimally invasive tool to follow-up cancer patients
over time, to detect minimal residual disease (MRD), to study metastasis-biology and …

International liquid biopsy standardization alliance white paper

D Connors, J Allen, JD Alvarez, J Boyle… - Critical reviews in …, 2020 - Elsevier
The promise of precision medicine as a model to customize health care to the individual
patient is heavily dependent upon new genetic tools to classify and characterize diseases …

Deep Learning-Assisted Assessing of Single Circulating Tumor Cell Viability via Cellular Morphology

Y Yang, Z Wang, T Hao, M Ye, J Li, Q Zhang… - Analytical …, 2024 - ACS Publications
Circulating tumor cells (CTCs) are closely associated with cancer metastasis and
recurrence, so the assessment of CTC viability is crucial for diagnosis, prognosis evaluation …

An electrochemical biosensor based on mild reduction-activated CRISPR/Cas12a system for sensitive detection of circulating tumor cells

L Sha, Y Cao, L Wang, Y Qin, S Zhu, J Zhao… - Biosensors and …, 2024 - Elsevier
Circulating tumor cell (CTC) has been a valuable biomarker for the diagnosis of breast
cancer, while folate receptor is a kind of cell surface receptor glycoprotein which is …

Label-free inertial-ferrohydrodynamic cell separation with high throughput and resolution

Y Liu, W Zhao, R Cheng, A Puig, J Hodgson, M Egan… - Lab on a Chip, 2021 - pubs.rsc.org
Rapid and label-free separation of target cells from biological samples provided unique
opportunity for disease diagnostics and treatment. However, even with advanced …

Simultaneous and Multimodal Antigen-Binding Profiling and Isolation of Rare Cells via Quantitative Ferrohydrodynamic Cell Separation

Y Liu, RMS Vieira, L Mao - ACS nano, 2022 - ACS Publications
Simultaneous cell profiling and isolation based on cellular antigen-binding capacity plays an
important role in understanding and treating diseases. However, fluorescence-activated cell …

Fundamentals of integrated ferrohydrodynamic cell separation in circulating tumor cell isolation

Y Liu, W Zhao, R Cheng, BN Harris, JR Murrow… - Lab on a Chip, 2021 - pubs.rsc.org
Methods to separate circulating tumor cells (CTCs) from blood samples were intensively
researched in order to understand the metastatic process and develop corresponding …

Functionalized tetrahedral DNA frameworks for the capture of circulating tumor cells

Y Chen, M Lin, D Ye, S Wang, X Zuo, M Li - Nature Protocols, 2024 - nature.com
Identification and characterization of circulating tumor cells (CTCs) from blood samples of
patients with cancer can help monitor parameters such as disease stage, disease …