Clostridioides difficile is a Gram-positive anaerobe that can cause a spectrum of disorders
that range in severity from mild diarrhoea to fulminant colitis and/or death. The bacterium …

Clostridium difficile is a major cause of intestinal infection and diarrhoea in individuals
following antibiotic treatment. Recent studies have begun to elucidate the mechanisms that …

Clostridium difficile is a bacterial pathogen that is the leading cause of nosocomial antibiotic-
associated diarrhea and pseudomembranous colitis worldwide. The incidence, severity …

Clostridioides difficile is the most common cause of nosocomial antibiotic-associated
diarrhea, and is responsible for a spectrum of diseases characterized by high levels of …

Abstract Epidemic C. difficile (027/BI/NAP1) has rapidly emerged in the past decade as the
leading cause of antibiotic-associated diarrhea worldwide. However, the key events in …

Bacteriophages, or simply phages, are viruses infecting bacteria. With an estimated 1031
particles in the biosphere, phages outnumber bacteria by a factor of at least 10 and not …

Clostridium difficile is the cause of antibiotics-associated diarrhea and pseudomembranous
colitis. The pathogen produces three protein toxins: C. difficile toxins A (TcdA) and B (TcdB) …

Clostridium difficile infection (CDI) has significant clinical impact especially on the elderly
and/or immunocompromised patients. The pathogenicity of Clostridium difficile is mainly …

Clostridium difficile is now considered to be one of the most important causes of health care-
associated infections. C. difficile infections are also emerging in the community and in …

Clostridium difficile is a formidable nosocomial and community-acquired pathogen, causing
clinical presentations ranging from asymptomatic colonization to self-limiting diarrhea to …