Candidiasis has increased substantially worldwide over recent decades and is a significant
cause of morbidity and mortality, especially among critically ill patients. Diabetes mellitus …

Invasive candidiasis (IC) is a leading cause of mycosis-associated mortality in the United
States. We examined data from the National Center for Health Statistics and reviewed recent …

The incidence of invasive mycoses is increasing, especially among patients who are
immunocompromised or hospitalized with serious underlying diseases. Such infections may …

Background The epidemiology of candidemia varies depending on the geographic region.
Little is known about the epidemiology of candidemia in Latin America. Methods We …

A substantial proportion of patients become colonised with Candida spp during hospital
stay, but only few subsequently develop severe infection. Clinical signs of severe infection …

Background Caspofungin is an echinocandin agent with fungicidal activity against candida
species. We performed a double-blind trial to compare caspofungin with amphotericin B …

Invasive fungal infections are increasingly common in the nosocomial setting. Furthermore,
because risk factors for these infections continue to increase in frequency, it is likely that …

We conducted a prospective, multicenter observational study of adults (n= 1447) and
children (n= 144) with candidemia at tertiary care centers in the United States in parallel with …

Candidemia studies have documented geographic differences in rates and epidemiology,
underscoring the need for surveillance to monitor trends. We conducted prospective …

The epidemiology of invasive fungal infection is evolving. Yeasts other than Candida
albicans and molds other than Aspergillus fumigatus have emerged as significant causes of …