Plant hormones are signalling compounds that regulate crucial aspects of growth,
development and environmental stress responses. Abiotic stresses, such as drought …

Mechanical force is an essential physical element that contributes to the formation and
function of life. The discovery of the evolutionarily conserved PIEZO family, including PIEZO1 …

Calcium (Ca2+) is a unique mineral that serves as both a nutrient and a signal in all
eukaryotes. To maintain Ca2+ homeostasis for both nutrition and signaling purposes, the …

Adverse variations of abiotic environmental cues that deviate from an optimal range impose
stresses to plants. Abiotic stresses severely impede plant physiology and development …

In plants, a variety of stimuli trigger long-range calcium signals that travel rapidly along the
vasculature to distal tissues via poorly understood mechanisms. Here, we use quantitative …

In animals, PIEZOs are plasma membrane–localized cation channels involved in diverse
mechanosensory processes. We investigated PIEZO function in tip-growing cells in the moss …

Many ion channels have been described as mechanosensitive according to various criteria.
Most broadly defined, an ion channel is called mechanosensitive if its activity is controlled by …

Mechanosensing is a ubiquitous process to translate external mechanical stimuli into
biological responses. Piezo1 ion channels are directly gated by mechanical forces and play …

Plants have evolved stress-sensing machineries that initiate rapid adaptive environmental
stress responses. Cytosolic calcium ion (Ca 2+) is the most prominent second messenger …

Piezo1 channels are essential mechanically activated ion channels in vertebrates. Their
selective activation by the synthetic chemical activator Yoda1 opened new avenues to probe …