Opinion statement Dengue viruses (DENV) continue to circulate worldwide, resulting in a
significant burden on human health. There are four antigenically distinct serotypes of DENV …

Infections with flaviviruses, such as dengue, West Nile virus and the recently re-emerging
Zika virus, are an increasing and probably lasting global risk. This Review summarizes and …

The flavivirus NS3 protein is associated with the endoplasmic reticulum membrane via its
close interaction with the central hydrophilic region of the NS2B integral membrane protein …

The ongoing COVID-19 pandemic, periodic recurrence of viral infections, and the
emergence of challenging variants has created an urgent need of alternative therapeutic …

Highlights•Evaluating drug efficacy, specificity and toxicity may help to develop an optimal
treatment regime for in vivo studies.•Measuring time to resolve viremia in vivo may help to …

Glycans are among the most important cell molecular components. However, given their
structural diversity, their functions have not been fully explored. Glycosylation is a vital post …

Glycoside trimming enzymes are crucially important in a broad range of metabolic pathways,
including glycoprotein and glycolipid processing and carbohydrate digestion in the intestinal …

Dengue virus (DV) is a mosquito‐borne flavivirus that causes haemorrhagic fever in
humans. DV primarily targets immature dendritic cells (DCs) after a bite by an infected …

Increased understanding of the role of protein-and lipid-linked carbohydrates in a wide
range of biological processes has led to interest in drugs that target the enzymes involved in …

Dengue fever is the most frequent arthropod-borne viral disease of humans, with almost half
of the world's population at risk of infection. The high prevalence, lack of an effective …