Left ventricular non-compaction cardiomyopathy

JA Towbin, A Lorts, JL Jefferies - The Lancet, 2015 - thelancet.com
Left ventricular non-compaction, the most recently classified form of cardiomyopathy, is
characterised by abnormal trabeculations in the left ventricle, most frequently at the apex. It …

Left ventricular noncompaction cardiomyopathy: cardiac, neuromuscular, and genetic factors

J Finsterer, C Stoellberger, JA Towbin - Nature Reviews Cardiology, 2017 - nature.com
Left ventricular hypertrabeculation (LVHT) or noncompaction is a myocardial abnormality of
unknown aetiology, frequently associated with monogenic disorders, particularly …

Cardiomyopathy phenotypes and outcomes for children with left ventricular myocardial noncompaction: results from the pediatric cardiomyopathy registry

JL Jefferies, JD Wilkinson, LA Sleeper, SD Colan… - Journal of cardiac …, 2015 - Elsevier
Background Left ventricular noncompaction (LVNC) is a distinct form of cardiomyopathy
characterized by hypertrabeculation of the left ventricle. The LVNC phenotype may occur in …

Key questions relating to left ventricular noncompaction cardiomyopathy: is the emperor still wearing any clothes?

RH Anderson, B Jensen, TJ Mohun… - Canadian Journal of …, 2017 - Elsevier
The evidence is increasing that left ventricular noncompaction cardiomyopathy as it is
currently defined does not represent a failure of compaction of pre-existing trabecular …

Pediatric cardiomyopathies: causes, epidemiology, clinical course, preventive strategies and therapies

SE Lipshultz, TR Cochran, DA Briston, SR Brown… - Future …, 2013 - Taylor & Francis
Pediatric cardiomyopathies, which are rare but serious disorders of the muscles of the heart,
affect at least one in every 100,000 children in the USA. Approximately 40% of children with …

Reproducibility of echocardiographic diagnosis of left ventricular noncompaction

SF Saleeb, R Margossian, CT Spencer… - Journal of the American …, 2012 - Elsevier
BACKGROUND: Left ventricular noncompaction (LVNC) cardiomyopathy is variably defined
by numerous trabeculations, deep intertrabecular recesses, and noncompacted-to …

Left ventricular noncompaction—a systematic review of risk factors in the pediatric population

K Łuczak-Woźniak, B Werner - Journal of Clinical Medicine, 2021 - mdpi.com
Left ventricular noncompaction (LVNC) is a heterogeneous, often hereditary group of
diseases, which may have diverse clinical manifestations. This article reviews the risk factors …

Interobserver agreement of the echocardiographic diagnosis of LV hypertrabeculation/noncompaction

C Stöllberger, B Gerecke, R Engberding… - Cardiovascular …, 2015 - jacc.org
Objectives The aim of the study was to assess interobserver agreement (IOA) between 3
observers from 2 laboratories. Background IOA of left ventricular hypertrabeculation …

[HTML][HTML] Semaphorin 3E/PlexinD1 signaling is required for cardiac ventricular compaction

R Sandireddy, DM Cibi, P Gupta, A Singh, N Tee… - JCI insight, 2019 - ncbi.nlm.nih.gov
Left ventricular noncompaction (LVNC) is one of the most common forms of genetic
cardiomyopathy characterized by excessive trabeculation and impaired myocardial …

State-of-the art review: Noncompaction cardiomyopathy in pediatric patients

S Rohde, R Muslem, E Kaya, M Dalinghaus… - Heart Failure …, 2022 - Springer
Noncompaction cardiomyopathy (NCCM) is a disease characterized by hypertrabeculation,
commonly hypothesized due to an arrest in compaction during fetal development. In 2006 …