Colorectal cancer (CRC), a leading cause of cancer-related death worldwide, evolves as a
result of the stepwise accumulation of a series of genetic and epigenetic alterations in the …

Inflammatory bowel disease (IBD) includes Crohn's disease (CD) and ulcerative colitis (UC).
These are chronic autoimmune diseases of unknown etiology affecting the gastrointestinal …

Objective miR-21 was found to be overexpressed in the colon tissues and serum of patients
with UC and colorectal cancer (CRC); however, the exact roles of miR-21 in colitis …

Inflammatory bowel diseases (IBD) are defined by the continuous inflammation of the
gastrointestinal tract. During inflammation, the number of pathogens in the intestinal …

Background Evidence suggests the central role of tumor necrosis factor (TNF)-α in the
pathomechanism of inflammatory bowel disease (IBD); however, its effect on epigenetic …

AIM To investigate the miRNA expression in colonic mucosal biopsies from endoscopically
inflamed and non inflamed regions of ulcerative colitis (UC) patients. METHODS Colonic …

Background Longstanding ulcerative colitis (UC) bears a high risk for development of UC-
associated colorectal carcinoma (UCC). The inflammatory microenvironment influences …

Inflammatory bowel diseases (IBD), mainly including Crohn's disease and ulcerative colitis,
are characterized by chronic inflammation of the gastrointestinal tract. Despite improvements …

Background Pancreatic cancer is an aggressive cancer with dismal prognosis, urgently
necessitating better biomarkers to improve therapeutic options and early diagnosis …

Gastric cancer is responsible for approximately one million annual deaths worldwide.
Recently, the important roles of miRNAs as vital factors in malignancy processes such as …