Ghrelin in psychiatric disorders–a review

DA Wittekind, M Kluge - Psychoneuroendocrinology, 2015 - Elsevier
Ghrelin is a 28-amino-acid peptide hormone, first described in 1999 and broadly expressed
in the organism. As the only known orexigenic hormone secreted in the periphery, it …

Clarifying the ghrelin system's ability to regulate feeding behaviours despite enigmatic spatial separation of the GHSR and its endogenous ligand

A Edwards, A Abizaid - International journal of molecular sciences, 2017 - mdpi.com
Ghrelin is a hormone predominantly produced in and secreted from the stomach. Ghrelin is
involved in many physiological processes including feeding, the stress response, and in …

[HTML][HTML] Peptidyl hormones of endocrine cells origin in the gut—Their discovery and physiological relevance

P Ceranowicz, Z Warzecha, A Dembinski - J. Physiol. Pharmacol, 2015 - jpp.krakow.pl
In 1902 William Bayliss and Ernest Starling discovered secretin and it was the beginning of
general endocrinology as well as, endocrinology of gastrointestinal tract. Ernest Starling was …

β‐Cell regeneration through the transdifferentiation of pancreatic cells: Pancreatic progenitor cells in the pancreas

HS Kim, MK Lee - Journal of diabetes investigation, 2016 - Wiley Online Library
Pancreatic progenitor cell research has been in the spotlight, as these cells have the
potential to replace pancreatic β‐cells for the treatment of type 1 and 2 diabetic patients with …

Butyrylcholinesterase regulates central ghrelin signaling and has an impact on food intake and glucose homeostasis

VP Chen, Y Gao, L Geng, S Brimijoin - International journal of obesity, 2017 - nature.com
Background: Ghrelin is the only orexigenic hormone known to stimulate food intake and
promote obesity and insulin resistance. We recently showed that plasma ghrelin is …

A significant role of the truncated ghrelin receptor GHS-R1b in ghrelin-induced signaling in neurons

G Navarro, D Aguinaga, E Angelats, M Medrano… - Journal of Biological …, 2016 - ASBMB
The truncated non-signaling ghrelin receptor growth hormone secretagogue R1b (GHS-
R1b) has been suggested to simply exert a dominant negative role in the trafficking and …

Protective and healing effects of ghrelin and risk of cancer in the digestive system

G Ginter, P Ceranowicz, Z Warzecha - International journal of molecular …, 2021 - mdpi.com
Ghrelin is an endogenous ligand for the ghrelin receptor, previously known as the growth
hormone secretagogue receptor. This hormone is mainly produced by endocrine cells …

The role of ghrelin in metabolic regulation

J Pinkney - Current Opinion in Clinical Nutrition & Metabolic Care, 2014 - journals.lww.com
Ghrelin functions primarily as a short-term metabolic switch at the onset of fasting, gearing
the fuel economy away from glucose uptake, conserving glucose for vital functions …

Ghrelin agonist does not foster insulin resistance but improves cognition in an Alzheimer's disease mouse model

N Kunath, T van Groen, DB Allison, A Kumar… - Scientific reports, 2015 - nature.com
The orexigenic hormone ghrelin, a potential antagonist of the insulin system, ensures
sufficient serum glucose in times of fasting. In the race for new therapeutics for diabetes, one …

Ghrelin Facilitates GLUT2-, SGLT1- and SGLT2-mediated Intestinal Glucose Transport in Goldfish (Carassius auratus)

AM Blanco, JI Bertucci, N Ramesh, MJ Delgado… - Scientific Reports, 2017 - nature.com
Glucose homeostasis is an important biological process that involves a variety of regulatory
mechanisms. This study aimed to determine whether ghrelin, a multifunctional gut-brain …