Understanding structure–function relationships of nanoadjuvants for enhanced cancer vaccine efficacy

J Tan, B Ding, B Teng, P Ma… - Advanced Functional …, 2022 - Wiley Online Library
Adjuvant, as an important part of vaccines, can observably enhance the magnitude, breadth
and durability of immune responses. Nanoadjuvants, as novel vaccine adjuvants, have …

Involvement of inflammation and its resolution in disease and therapeutics

S Alfaro, V Acuña, R Ceriani, MF Cavieres… - International Journal of …, 2022 - mdpi.com
Inflammation plays a critical role in the response to and survival from injuries and/or
infections. It occurs in two phases: initiation and resolution; however, when these events do …

[HTML][HTML] Efficacy and safety of immunological adjuvants. Where is the cut-off?

A Batista-Duharte, DT Martínez, IZ Carlos - Biomedicine & …, 2018 - Elsevier
Research over the past several decades has provided insight into the mode of action of
adjuvants. However, the main focus of attention has been the efficacy in the induction of …

The hen's egg test on chorioallantoic membrane: An alternative assay for the assessment of the irritating effect of vaccine adjuvants

A Batista-Duharte, G Jorge Murillo… - International …, 2016 - journals.sagepub.com
Local reactions are the most frequent adverse event associated with vaccines. Adjuvants are
major constituents of many vaccines and they are frequently involved in these reactions …

Adjuvants are key factors for the development of future vaccines: lessons from the Finlay adjuvant platform

O Pérez, B Romeu, O Cabrera, E González… - Frontiers in …, 2013 - frontiersin.org
The development of effective vaccines against neglected diseases, especially those
associated with poverty and social deprivation, is urgently needed. Modern vaccine …

Laser vaccine adjuvants: History, progress, and potential

S Kashiwagi, T Brauns, J Gelfand… - Human vaccines & …, 2014 - Taylor & Francis
Immunologic adjuvants are essential for current vaccines to maximize their efficacy.
Unfortunately, few have been found to be sufficiently effective and safe for regulatory …

[HTML][HTML] Laser adjuvant for vaccination

S Kashiwagi - FASEB journal: official publication of the Federation …, 2020 - ncbi.nlm.nih.gov
The use of an immunologic adjuvant to augment the immune response is essential for
modern vaccines which are relatively ineffective on their own. In the past decade …

Comparative efficacy and toxicity of two vaccine candidates against Sporothrix schenckii using either Montanide™ Pet Gel A or aluminum hydroxide adjuvants in mice

DL Portuondo, A Batista-Duharte, LS Ferreira… - Vaccine, 2017 - Elsevier
Sporotrichosis is an important zoonosis in Brazil and the most frequent subcutaneous
mycosis in Latin America, caused by different Sporothrix species. Currently, there is no …

Adjuvants and delivery systems for antifungal vaccines: current state and future developments

DLF Portuondo, LS Ferreira, AC Urbaczek… - …, 2014 - academic.oup.com
Mycoses are gaining increasing attention in modern medicine because of the increase in
diseases associated with opportunistic fungal infections. Despite the recognized role of the …

Systemic immunotoxicity reactions induced by adjuvanted vaccines

A Batista-Duharte, D Portuondo, O Perez… - International …, 2014 - Elsevier
Vaccine safety is a topic of concern for the treated individual, the family, the health care
personnel, and the others involved in vaccination programs as recipients or providers …