Aryl transfer strategies mediated by photoinduced electron transfer

AR Allen, EA Noten, CRJ Stephenson - Chemical reviews, 2021 - ACS Publications
Radical aryl migrations are powerful techniques to forge new bonds in aromatic compounds.
The growing popularity of photoredox catalysis has led to an influx of novel strategies to …

From antibacterial to antitumour agents: a brief review on the chemical and medicinal aspects of sulfonamides

H Azevedo-Barbosa, DF Dias, LL Franco… - Mini Reviews in …, 2020 - ingentaconnect.com
Sulfonamides have been in clinical use for many years, and the development of bioactive
substances containing the sulfonamide subunit has grown steadily in view of their important …

New pyrimidine and pyrazole-based compounds as potential EGFR inhibitors: Synthesis, anticancer, antimicrobial evaluation and computational studies

IMM Othman, ZM Alamshany, NY Tashkandi… - Bioorganic …, 2021 - Elsevier
This study was focused on the synthesis of new pyrimidines 4a, b, 5a, b and pyrazoles 6a, b
as ATP mimicking tyrosine kinase inhibitors of the epidermal growth factor receptor (EGFR) …

Synthesis, biological evaluation, and molecular docking of novel azolylhydrazonothiazoles as potential anticancer agents

JY Al-Humaidi, SM Gomha, SM Riyadh, MS Ibrahim… - ACS …, 2023 - ACS Publications
A novel set of thiazolylhydrazonothiazoles bearing an indole moiety were synthesized by
subjection reactions of carbothioamide derivative and hydrazonoyl chlorides (or α …

Synthesis, characterization and biological activities of new Schiff base compound and its lanthanide complexes

AA Abu-Yamin, MS Abduh, SAM Saghir, N Al-Gabri - Pharmaceuticals, 2022 - mdpi.com
The thermal condensation of 3-(2-Furyl) acrolein with 2-Amino-6-ethoxybenzothiazole
generated a new Schiff base,(1E, 2E)-N-(6-ethoxybenzo [d] thiazol-2-yl)-3-(furan-2-yl) prop …

Discovery of novel pyridazine-tethered sulfonamides as carbonic anhydrase II inhibitors for the management of glaucoma

HO Tawfik, MM Saleh, A Ammara… - Journal of Medicinal …, 2024 - ACS Publications
As a progressive neuropathic condition, glaucoma can cause lifelong blindness if left
untreated. Novel phenylpyridazine-tethered sulfonamides were designed as selective …

Novel 4/3-((4-oxo-5-(2-oxoindolin-3-ylidene) thiazolidin-2-ylidene) amino) benzenesulfonamides: Synthesis, carbonic anhydrase inhibitory activity, anticancer activity …

WM Eldehna, MF Abo-Ashour, A Nocentini… - European journal of …, 2017 - Elsevier
Herein we report the synthesis of two series of novel 4/3-((4-oxo-5-(2-oxoindolin-3-ylidene)
thiazolidin-2-ylidene) amino) benzenesulfonamides (4a-m and 7a-g). All the newly prepared …

Design and synthesis of ciprofloxacin-sulfonamide hybrids to manipulate ciprofloxacin pharmacological qualities: Potency and side effects

NM Ibrahim, SH Fahim, M Hassan, AE Farag… - European Journal of …, 2022 - Elsevier
Fluoroquinolones are a class of antibacterial agents used clinically to treat a wide array of
bacterial infections. Although being potent, susceptibility to CNS side effects limits their use …

Sulfaguanidine hybrid with some new pyridine-2-one derivatives: Design, synthesis, and antimicrobial activity against multidrug-resistant bacteria as dual DNA gyrase …

A Ragab, SA Fouad, OAA Ali, EM Ahmed, AM Ali… - Antibiotics, 2021 - mdpi.com
Herein, a series of novel hybrid sulfaguanidine moieties, bearing 2-cyanoacrylamide 2a–d,
pyridine-2-one 3–10, and 2-imino-2 H-chromene-3-carboxamide 11, 12 derivatives, were …

Visible light amination/Smiles cascade: access to phthalazine derivatives

E Brachet, L Marzo, M Selkti, B König, P Belmont - Chemical Science, 2016 - pubs.rsc.org
We report the synthesis of various phthalazines via a new cascade reaction, initiated by
visible light photocatalysis, involving a radical hydroamination reaction followed by a radical …