A Novel Actin Binding Drug with In Vivo Efficacy

A Ravichandran, M Geng, KG Hull, J Li… - Antimicrobial agents …, 2019 - Am Soc Microbiol
Occidiofungin is produced by the soil bacterium Burkolderia contaminans MS14 and is
structurally similar or identical to the burkholdines, xylocandins, and cepacidines. This study …

Visualizing the in vitro assembly of tropomyosin/actin filaments using TIRF microscopy

M Janco, I Dedova, NS Bryce, EC Hardeman… - Biophysical …, 2020 - Springer
Tropomyosins are elongated alpha-helical proteins that form co-polymers with most actin
filaments within a cell and play important roles in the structural and functional diversification …

Tropomyosin concentration but not formin nucleators mDia1 and mDia3 determines the level of tropomyosin incorporation into actin filaments

JCM Meiring, NS Bryce, JLG Niño, A Gabriel, SS Tay… - Scientific reports, 2019 - nature.com
The majority of actin filaments in human cells exist as a co-polymer with tropomyosin, which
determines the functionality of actin filaments in an isoform dependent manner. Tropomyosin …

Growth factor modulation of TGF-beta (TGF-β)-induced epithelial-to-mesenchymal transition (EMT) in the eye lens

M Flokis - 2024 - ses.library.usyd.edu.au
The eye lens is a transparent organ dependent on growth factors within the ocular media (eg
FGF) to regulate its normal functionality. During stress &/or inflammation, activation of …