Neuronal cell death

M Fricker, AM Tolkovsky, V Borutaite… - Physiological …, 2018 - journals.physiology.org
Neuronal cell death occurs extensively during development and pathology, where it is
especially important because of the limited capacity of adult neurons to proliferate or be …

[HTML][HTML] Role of plant derived alkaloids and their mechanism in neurodegenerative disorders

G Hussain, A Rasul, H Anwar, N Aziz… - … journal of biological …, 2018 - ncbi.nlm.nih.gov
Neurodegenerative diseases are conventionally demarcated as disorders with selective loss
of neurons. Conventional as well as newer molecules have been tested but they offer just …

Carnosine as an effective neuroprotector in brain pathology and potential neuromodulator in normal conditions

DS Berezhnoy, SL Stvolinsky, AV Lopachev… - Amino acids, 2019 - Springer
Abstract Carnosine (b-alanyl-l-histidine) is an endogenous dipeptide widely distributed in
excitable tissues, such as muscle and neural tissues—though in minor concentrations in the …

Molecular Mechanisms and Therapeutic Potential of α-and β-Asarone in the Treatment of Neurological Disorders

R Balakrishnan, DY Cho, IS Kim, SH Seol, DK Choi - Antioxidants, 2022 - mdpi.com
Neurological disorders are important causes of morbidity and mortality around the world.
The increasing prevalence of neurological disorders, associated with an aging population …

Role of imaging in early diagnosis of acute ischemic stroke: a literature review

MA Akbarzadeh, S Sanaie… - The Egyptian Journal of …, 2021 - Springer
Stroke is a serious health condition that is responsible for more than 5% of total deaths. Near
20% of patients experiencing stroke die every year, resulting in the stroke being at the top of …

Ischemic stroke, lessons from the past towards effective preclinical models

B Amado, L Melo, R Pinto, A Lobo, P Barros, JR Gomes - Biomedicines, 2022 - mdpi.com
Ischemic stroke is a leading cause of death worldwide, mainly in western countries. So far,
approved therapies rely on reperfusion of the affected brain area, by intravenous …

The interplay of microRNAs and post-ischemic glutamate excitotoxicity: an emergent research field in stroke medicine

A Majdi, J Mahmoudi, S Sadigh-Eteghad… - Neurological …, 2016 - Springer
Stroke is the second leading cause of death and the most common cause of adult disabilities
among elderlies. It involves a complex series of mechanisms among which, excitotoxicity is …

Is selenium supplementation beneficial in acute ischemic stroke?

M Ramezani, L Simani, S Abedi, H Pakdaman - The neurologist, 2022 - journals.lww.com
Background: Selenium (Se) plays a significant role in brain physiology. The existing human
data demonstrate that stroke is associated with significantly reduced Se levels and …

Exploring the risk factors and possible role of calcium in infective endocarditis

YS Kuo, YM Tsai - Diagnostics, 2023 - mdpi.com
Infective endocarditis (IE) is a severe and potentially life-threatening infection that affects the
endocardium, the inner lining of the heart chambers and valves. Although rare, it is a …

Ceramides and sphingosine-1-phosphate as potential markers in diagnosis of ischaemic stroke

A Fiedorowicz, A Kozak-Sykała… - Neurologia i …, 2019 - journals.viamedica.pl
Background. Brain imaging in stroke diagnostics is a powerful tool, but one that can fail in
more challenging cases, and one that is not particularly useful in identifying transient …