Latent mutations in the ancestries of alleles under selection

WTL Fan, J Wakeley - Theoretical Population Biology, 2024 - Elsevier
We consider a single genetic locus with two alleles A 1 and A 2 in a large haploid
population. The locus is subject to selection and two-way, or recurrent, mutation. Assuming …

Large-sample analysis of cost functionals for inference under the coalescent

M Favero, J Koskela - arXiv preprint arXiv:2412.06004, 2024 - arxiv.org
The coalescent is a foundational model of latent genealogical trees under neutral evolution,
but suffers from intractable sampling probabilities. Methods for approximating these …

Weak convergence of the scaled jump chain and number of mutations of the Kingman coalescent

M Favero, H Hult - Electronic Journal of Probability, 2024 - projecteuclid.org
The Kingman coalescent is a fundamental process in population genetics modelling the
ancestry of a sample of individuals backwards in time. In this paper, in a large-sample-size …