Past, present, and future of radiation-induced cardiotoxicity: refinements in targeting, surveillance, and risk stratification
C Bergom, JA Bradley, AK Ng, P Samson, C Robinson… - Cardio Oncology, 2021 - jacc.org
Radiation therapy is an important component of cancer therapy for many malignancies. With
improvements in cardiac-sparing techniques, radiation-induced cardiac dysfunction has …
improvements in cardiac-sparing techniques, radiation-induced cardiac dysfunction has …
[HTML][HTML] Cardiac toxicity of thoracic radiotherapy: existing evidence and future directions
The impact of radiotherapy on the heart has become an area of interest in recent years.
Many different cardiac dose-volume constraints have been associated with cardiac toxicity …
Many different cardiac dose-volume constraints have been associated with cardiac toxicity …
Association of left anterior descending coronary artery radiation dose with major adverse cardiac events and mortality in patients with non–small cell lung cancer
KM Atkins, TL Chaunzwa, N Lamba… - JAMA …, 2021 - jamanetwork.com
Importance Radiotherapy accelerates coronary heart disease (CHD), but the dose to critical
cardiac substructures has not been systematically studied in lung cancer. Objective To …
cardiac substructures has not been systematically studied in lung cancer. Objective To …
Medical physics challenges in clinical MR-guided radiotherapy
The integration of magnetic resonance imaging (MRI) for guidance in external beam
radiotherapy has faced significant research and development efforts in recent years. The …
radiotherapy has faced significant research and development efforts in recent years. The …
Organs at risk radiation dose constraints
G Noël, D Antoni - Cancer/radiothérapie, 2022 - Elsevier
Dose constraints are essential for performing dosimetry, especially for intensity modulation
and for radiotherapy under stereotaxic conditions. We present the update of the …
and for radiotherapy under stereotaxic conditions. We present the update of the …
[HTML][HTML] Radiotherapy-related lymphopenia affects overall survival in patients with lung cancer
A Abravan, C Faivre-Finn, J Kennedy… - Journal of Thoracic …, 2020 - Elsevier
Introduction Lymphopenia after radiotherapy has an adverse effect on the patient's outcome.
However, the relationship between radiotherapy dose delivery and lymphopenia is not fully …
However, the relationship between radiotherapy dose delivery and lymphopenia is not fully …
Nuts and bolts of 4D-MRI for radiotherapy
B Stemkens, ES Paulson… - Physics in Medicine & …, 2018 - iopscience.iop.org
Magnetic resonance imaging (MRI) is increasingly being used in the radiotherapy workflow
because of its superior soft tissue contrast and high flexibility in contrast. In addition to …
because of its superior soft tissue contrast and high flexibility in contrast. In addition to …
Association of sinoatrial node radiation dose with atrial fibrillation and mortality in patients with lung cancer
Importance Atrial fibrillation (AF) can develop following thoracic irradiation. However, the
critical cardiac substructure responsible for AF has not been properly studied. Objective To …
critical cardiac substructure responsible for AF has not been properly studied. Objective To …
[HTML][HTML] Demystifying the results of RTOG 0617: identification of dose sensitive cardiac subregions associated with overall survival
Introduction The RTOG 0617 trial presented a worse survival for patients with lung cancer
treated in the high-dose (74 Gy) arm. In multivariable models, radiation level and whole …
treated in the high-dose (74 Gy) arm. In multivariable models, radiation level and whole …
[HTML][HTML] Novel methodology to investigate the effect of radiation dose to heart substructures on overall survival
Purpose For patients with lung cancer treated with radiation therapy, a dose to the heart is
associated with excess mortality; however, it is often not feasible to spare the whole heart …
associated with excess mortality; however, it is often not feasible to spare the whole heart …