Gut bacteria and neurotransmitters

LMT Dicks - Microorganisms, 2022 - mdpi.com
Gut bacteria play an important role in the digestion of food, immune activation, and
regulation of entero-endocrine signaling pathways, but also communicate with the central …

The mechanisms and functions of spontaneous neurotransmitter release

ET Kavalali - Nature Reviews Neuroscience, 2015 - nature.com
Fast synaptic communication in the brain requires synchronous vesicle fusion that is evoked
by action potential-induced Ca2+ influx. However, synaptic terminals also release …

Molecular mechanisms for synchronous, asynchronous, and spontaneous neurotransmitter release

PS Kaeser, WG Regehr - Annual review of physiology, 2014 - annualreviews.org
Most neuronal communication relies upon the synchronous release of neurotransmitters,
which occurs through synaptic vesicle exocytosis triggered by action potential invasion of a …

The neuroscience of tinnitus

JJ Eggermont, LE Roberts - Trends in neurosciences, 2004 - cell.com
Tinnitus is an auditory phantom sensation (ringing of the ears) experienced when no
external sound is present. Most but not all cases are associated with hearing loss induced …

Synaptic vesicle recycling: steps and principles

SO Rizzoli - The EMBO journal, 2014 - embopress.org
Synaptic vesicle recycling is one of the best‐studied cellular pathways. Many of the proteins
involved are known, and their interactions are becoming increasingly clear. However, as for …

Thinking outside the cleft to understand synaptic activity: contribution of the cystine-glutamate antiporter (system xc−) to normal and pathological glutamatergic …

R Bridges, V Lutgen, D Lobner, DA Baker… - Pharmacological …, 2012 - Elsevier
Abstract System xc− represents an intriguing target in attempts to understand the
pathological states of the central nervous system. Also called a cystine-glutamate antiporter …

Differential triggering of spontaneous glutamate release by P/Q-, N- and R-type Ca2+ channels

YS Ermolyuk, FG Alder, R Surges, IY Pavlov… - Nature …, 2013 - nature.com
The role of voltage-gated Ca2+ channels (VGCCs) in spontaneous miniature
neurotransmitter release is incompletely understood. We found that stochastic opening of …

[HTML][HTML] Spatially non-overlapping Ca2+ signals drive distinct forms of neurotransmission

CS Wang, LM Monteggia, ET Kavalali - Cell reports, 2023 - cell.com
Summary Calcium (Ca 2+) signaling is tightly regulated within a presynaptic bouton. Here,
we visualize Ca 2+ signals within hippocampal presynaptic boutons using GCaMP8s tagged …

Hearing loss, hyperacusis, or tinnitus: what is modeled in animal research?

JJ Eggermont - Hearing research, 2013 - Elsevier
Animal models of tinnitus require a behavioral correlate thereof. Various conditioned
response methods and gap-startle reflex methods are in use and the outcomes generally …

Reelin mobilizes a VAMP7-dependent synaptic vesicle pool and selectively augments spontaneous neurotransmission

M Bal, J Leitz, AL Reese, DMO Ramirez… - Neuron, 2013 - cell.com
Reelin is a glycoprotein that is critical for proper layering of neocortex during development
as well as dynamic regulation of glutamatergic postsynaptic signaling in mature synapses …